CD12255

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12255

CD12255

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Comt

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• catechol-O-methyltransferase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• catechol-O-methyltransferase
• catechol O-methyltransferase
• catechol-O-methyltransferase 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Comt1
• D330014B15Rik
• D16Wsu103e

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12846

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• catechol-O-methyltransferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88470

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007744
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001111062
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001111063

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000000326

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.100940

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=116790

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• http://rdf.ncbi.nlm.nih.gov/pubmed/20976038
• Zhengsheng. Li, et.al., A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20808911
• S K. Segall, et.al., Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice., Genes, brain, and behavior, 2010, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/20659173
• R S. Yeung, et.al., The Vpreb1 and comt genes are closely linked and sublocalized to rat chromosome 11q23., Mammalian genome : official journal of the International Mammalian Genome Society, 1996, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9162259
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• R S. Yeung, et.al., Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10., Proceedings of the National Academy of Sciences of the United States of America, 1993, 90
  http://rdf.ncbi.nlm.nih.gov/pubmed/8103600
• M. Bućan, et.al., Comparative mapping of 9 human chromosome 22q loci in the laboratory mouse., Human molecular genetics, 1993, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/8401507
• N. Galili, et.al., A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region., Genome research, 1997, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9037598
• C M. Pauken, et.al., Molecular cloning, expression analysis, and chromosomal localization of mouse Hmg1-containing sequences., Mammalian genome : official journal of the International Mammalian Genome Society, 1994, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/8180479
• Mikko. Käenmäki, et.al., Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice., Journal of neurochemistry, 2010, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/20626558

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• catechol O-methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0016206
• catechol-containing compound metabolic process
  http://purl.obolibrary.org/obo/GO_0009712
• negative regulation of dopamine metabolic process
  http://purl.obolibrary.org/obo/GO_0045963
• intracellular membrane-bounded organelle
  http://purl.obolibrary.org/obo/GO_0043231
• positive regulation of homocysteine metabolic process
  http://purl.obolibrary.org/obo/GO_0050668
• negative regulation of smooth muscle cell proliferation
  http://purl.obolibrary.org/obo/GO_0048662
• female pregnancy
  http://purl.obolibrary.org/obo/GO_0007565
• dopamine metabolic process
  http://purl.obolibrary.org/obo/GO_0042417
• dopamine catabolic process
  http://purl.obolibrary.org/obo/GO_0042420
• methylation
  http://purl.obolibrary.org/obo/GO_0032259
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• estrogen metabolic process
  http://purl.obolibrary.org/obo/GO_0008210
• learning
  http://purl.obolibrary.org/obo/GO_0007612
• response to pain
  http://purl.obolibrary.org/obo/GO_0048265
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• multicellular organismal reproductive process
  http://purl.obolibrary.org/obo/GO_0048609
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0008168

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map04728
• http://www.genome.jp/dbget-bin/www_bget?map00350
• http://www.genome.jp/dbget-bin/www_bget?map00140

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Tyrosine metabolism
• Metabolic pathways
• Dopaminergic synapse
• Steroid hormone biosynthesis