CD12321

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12321

CD12321

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• S1pr5

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• sphingosine-1-phosphate receptor 5

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• S1P receptor 5
• sphingosine 1-phosphate receptor Edg-8
• sphingosine 1-phosphate receptor 5
• sphingosine-1-phosphate receptor 5
• S1P receptor Edg-8
• endothelial differentiation G-protein-coupled receptor 8
• sphingosine-1-phosphate receptor LPB4
• endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
• lysophospholipid receptor B4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• S1P5
• Edg8
• lpB4

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/94226

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• sphingosine-1-phosphate receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:2150641

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_053190

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000045087

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.190619

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605146

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• I. Ishii, et.al., Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11443127
• H. Meng, et.al., Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system., Developmental dynamics : an official publication of the American Association of Anatomists, 2009, 238
  http://rdf.ncbi.nlm.nih.gov/pubmed/19161225
• Volker. Brinkmann, et.al., The immune modulator FTY720 targets sphingosine 1-phosphate receptors., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11967257
• D S. Im, et.al., Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors., Biochemistry, 2001, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/11705398
• Alayna. Rodgers, et.al., Sphingosine 1-phosphate regulation of extracellular signal-regulated kinase-1/2 in embryonic stem cells., Stem cells and development, 2009, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/19228106
• R Jason. Kirby, et.al., Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney., American journal of physiology. Renal physiology, 2009, 296
  http://rdf.ncbi.nlm.nih.gov/pubmed/19073640
• Hideyo. Ohuchi, et.al., Expression patterns of the lysophospholipid receptor genes during mouse early development., Developmental dynamics : an official publication of the American Association of Anatomists, 2008, 237
  http://rdf.ncbi.nlm.nih.gov/pubmed/18924241
• Craig N. Jenne, et.al., T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19808259
• Isao. Ishii, et.al., Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/12006579
• Christine. McGiffert, et.al., Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis., FEBS letters, 2002, 531
  http://rdf.ncbi.nlm.nih.gov/pubmed/12401212

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• sphingosine-1-phosphate receptor activity
  http://purl.obolibrary.org/obo/GO_0038036
• G-protein coupled receptor activity
  http://purl.obolibrary.org/obo/GO_0004930

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04080

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Neuroactive ligand-receptor interaction