CD12400

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12400

CD12400

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mfn1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• mitofusin 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• transmembrane GTPase MFN1
• mitofusin 1
• mitofusin-1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 6330416C07Rik
• HR2
• 2310002F04Rik
• D3Ertd265e
• mKIAA4032

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/67414

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• mitofusin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914664

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_024200

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000027668

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.290414

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=608506

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Manuel. Rojo, et.al., Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo., Journal of cell science, 2002, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/11950885
• Zhiyin. Song, et.al., Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion., Molecular biology of the cell, 2009, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/19477917
• Sara. Cipolat, et.al., OPA1 requires mitofusin 1 to promote mitochondrial fusion., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/15509649
• Sajjan. Koirala, et.al., Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes., The Journal of cell biology, 2010, 191
  http://rdf.ncbi.nlm.nih.gov/pubmed/21149566
• Hsiuchen. Chen, et.al., Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development., The Journal of cell biology, 2003, 160
  http://rdf.ncbi.nlm.nih.gov/pubmed/12527753
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Naotada. Ishihara, et.al., Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice., Nature cell biology, 2009, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/19578372
• Hsiuchen. Chen, et.al., Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations., Cell, 2010, 141
  http://rdf.ncbi.nlm.nih.gov/pubmed/20403324
• Hsiuchen. Chen, et.al., Disruption of fusion results in mitochondrial heterogeneity and dysfunction., The Journal of biological chemistry, 2005, 280
  http://rdf.ncbi.nlm.nih.gov/pubmed/15899901
• Takumi. Koshiba, et.al., Structural basis of mitochondrial tethering by mitofusin complexes., Science (New York, N.Y.), 2004, 305
  http://rdf.ncbi.nlm.nih.gov/pubmed/15297672

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• GTPase activity
  http://purl.obolibrary.org/obo/GO_0003924
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• GTP binding
  http://purl.obolibrary.org/obo/GO_0005525
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• mitochondrial outer membrane
  http://purl.obolibrary.org/obo/GO_0005741
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• mitochondrial fusion
  http://purl.obolibrary.org/obo/GO_0008053

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName