CD12618

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12618

CD12618

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ctsk

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• cathepsin K

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• minisatellite 10q detected by probe MMS10
• cathepsin K

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI323530
• MMS10-Q
• Ms10q
• catK
• Cat K

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13038

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• cathepsin K
  http://metadb.riken.jp/db/mgi_rdf/MGI:107823

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007802

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000028111

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.272085

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601105

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Chang. Yang, et.al., NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/21151480
• Pierre. Moffatt, et.al., Hyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone development., Developmental dynamics : an official publication of the American Association of Anatomists, 2011, 240
  http://rdf.ncbi.nlm.nih.gov/pubmed/21246657
• J. Rantakokko, et.al., Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development., FEBS letters, 1996, 393
  http://rdf.ncbi.nlm.nih.gov/pubmed/8814310
• Michael L. Sohaskey, et.al., Osteopotentia regulates osteoblast maturation, bone formation, and skeletal integrity in mice., The Journal of cell biology, 2010, 189
  http://rdf.ncbi.nlm.nih.gov/pubmed/20440000
• Yuji. Ito, et.al., Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20501942
• B D. Gelb, et.al., Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency., Science (New York, N.Y.), 1996, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/8703060
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• R A. Dodds, et.al., Cathepsin K mRNA detection is restricted to osteoclasts during fetal mouse development., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/9556067
• B D. Gelb, et.al., Cathepsin K: isolation and characterization of the murine cDNA and genomic sequence, the homologue of the human pycnodysostosis gene., Biochemical and molecular medicine, 1996, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/8986645
• J W. Smit, et.al., Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption., Hepatology (Baltimore, Md.), 1998, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/9537446

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• bone resorption
  http://purl.obolibrary.org/obo/GO_0045453
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• lysosome
  http://purl.obolibrary.org/obo/GO_0005764
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• cysteine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004197
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• cysteine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008234

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04620
• http://www.genome.jp/dbget-bin/www_bget?map04380
• http://www.genome.jp/dbget-bin/www_bget?map04142
• http://www.genome.jp/dbget-bin/www_bget?map05323

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Toll-like receptor signaling pathway
• Rheumatoid arthritis
• Osteoclast differentiation
• Lysosome