CD12716

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12716

CD12716

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Arhgap5

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• Rho GTPase activating protein 5

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• rho GTPase-activating protein 5
• Rho GTPase activating protein 5
• rho-type GTPase-activating protein 5

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• p190-B

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/11855

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• Rho GTPase activating protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1332637

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009706

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000035133

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.35059
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.474991

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602680

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Brandy M. Heckman, et.al., Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development., Developmental biology, 2007, 309
  http://rdf.ncbi.nlm.nih.gov/pubmed/17662267
• Raffaella. Sordella, et.al., Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis., Cell, 2003, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/12705864
• Daniel S T. Hughes, et.al., Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation., BMC developmental biology, 2009, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/19463158
• Y. Piao, et.al., Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method., Genome research, 2001, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/11544199
• Haiming. Xu, et.al., Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential., Blood, 2009, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/19713466
• Raffaella. Sordella, et.al., Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development., Developmental cell, 2002, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/12015964
• Axel. Visel, et.al., Regulatory pathway analysis by high-throughput in situ hybridization., PLoS genetics, 2007, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/17953485
• Geetika. Chakravarty, et.al., p190-B RhoGAP regulates mammary ductal morphogenesis., Molecular endocrinology (Baltimore, Md.), 2003, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12637587
• Brandy M. Heckman-Stoddard, et.al., Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression., Breast cancer research : BCR, 2009, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/19703301
• P D. Burbelo, et.al., Cloning, genomic organization and chromosomal assignment of the mouse p190-B gene., Biochimica et biophysica acta, 1998, 1443
  http://rdf.ncbi.nlm.nih.gov/pubmed/9838117

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• SH2 domain binding
  http://purl.obolibrary.org/obo/GO_0042169
• regulation of cell size
  http://purl.obolibrary.org/obo/GO_0008361
• GTP binding
  http://purl.obolibrary.org/obo/GO_0005525
• positive regulation of GTPase activity
  http://purl.obolibrary.org/obo/GO_0043547
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• positive regulation of mesenchymal cell proliferation
  http://purl.obolibrary.org/obo/GO_0002053
• mammary gland development
  http://purl.obolibrary.org/obo/GO_0030879
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• small GTPase mediated signal transduction
  http://purl.obolibrary.org/obo/GO_0007264
• positive regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030335
• GTPase activator activity
  http://purl.obolibrary.org/obo/GO_0005096

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04670
• http://www.genome.jp/dbget-bin/www_bget?map04510

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Focal adhesion
• Leukocyte transendothelial migration