CD12732

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12732

CD12732

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Tgfb2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• transforming growth factor, beta 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• transforming growth factor beta-2
• TGF-beta-2
• transforming growth factor, beta 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• BB105277
• Tgfb-2
• Tgf-beta2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/21808

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• transforming growth factor, beta 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:98726

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009367

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000039239

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.18213

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=190220

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K. Manova, et.al., Expression of activins and TGF beta 1 and beta 2 RNAs in early postimplantation mouse embryos and uterine decidua., Mechanisms of development, 1992, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/1373953
• S K. Das, et.al., Expression of transforming growth factor-beta isoforms (beta 2 and beta 3) in the mouse uterus: analysis of the periimplantation period and effects of ovarian steroids., Endocrinology, 1992, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/1375903
• M W. Ferguson, et.al., Differential expression of insulin-like growth factors I and II (IGF I and II), mRNA, peptide and binding protein 1 during mouse palate development: comparison with TGF beta peptide distribution., Journal of anatomy, 1992, 181 ( Pt 2)
  http://rdf.ncbi.nlm.nih.gov/pubmed/1284245
• Yosuke. Funato, et.al., Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive dishevelled protein., Current biology : CB, 2010, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/20970343
• Chirag A. Shah, et.al., HoxA10 regulates transcription of the gene encoding transforming growth factor beta2 (TGFbeta2) in myeloid cells., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21087928
• Cristina M. Alvira, et.al., Inhibition of transforming growth factor β worsens elastin degradation in a murine model of Kawasaki disease., The American journal of pathology, 2011, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/21356372
• Luis. Luna-Zurita, et.al., Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890042
• Vesna. Todorovic, et.al., Long form of latent TGF-β binding protein 1 (Ltbp1L) regulates cardiac valve development., Developmental dynamics : an official publication of the American Association of Anatomists, 2011, 240
  http://rdf.ncbi.nlm.nih.gov/pubmed/21181942
• M. Taketo, et.al., Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/1543915
• B C. Paria, et.al., Localization and binding of transforming growth factor-beta isoforms in mouse preimplantation embryos and in delayed and activated blastocysts., Developmental biology, 1992, 151
  http://rdf.ncbi.nlm.nih.gov/pubmed/1577201

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• ventricular septum morphogenesis
  http://purl.obolibrary.org/obo/GO_0060412
• response to progesterone
  http://purl.obolibrary.org/obo/GO_0032570
• positive regulation of neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0043525
• epithelial to mesenchymal transition
  http://purl.obolibrary.org/obo/GO_0001837
• neuron development
  http://purl.obolibrary.org/obo/GO_0048666
• regulation of transforming growth factor beta2 production
  http://purl.obolibrary.org/obo/GO_0032909
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• beta-amyloid binding
  http://purl.obolibrary.org/obo/GO_0001540
• growth
  http://purl.obolibrary.org/obo/GO_0040007
• wound healing
  http://purl.obolibrary.org/obo/GO_0042060
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• neuron fate commitment
  http://purl.obolibrary.org/obo/GO_0048663
• extracellular matrix
  http://purl.obolibrary.org/obo/GO_0031012
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• negative regulation of macrophage cytokine production
  http://purl.obolibrary.org/obo/GO_0010936
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• positive regulation of heart contraction
  http://purl.obolibrary.org/obo/GO_0045823
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• trans-Golgi network
  http://purl.obolibrary.org/obo/GO_0005802
• positive regulation of phosphatidylinositol 3-kinase signaling
  http://purl.obolibrary.org/obo/GO_0014068
• cell morphogenesis
  http://purl.obolibrary.org/obo/GO_0000902
• hair follicle development
  http://purl.obolibrary.org/obo/GO_0001942
• cardiac muscle cell proliferation
  http://purl.obolibrary.org/obo/GO_0060038
• negative regulation of immune response
  http://purl.obolibrary.org/obo/GO_0050777
• regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0042981
• skeletal system development
  http://purl.obolibrary.org/obo/GO_0001501
• positive regulation of epithelial to mesenchymal transition
  http://purl.obolibrary.org/obo/GO_0010718
• eye development
  http://purl.obolibrary.org/obo/GO_0001654
• heart morphogenesis
  http://purl.obolibrary.org/obo/GO_0003007
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• pathway-restricted SMAD protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0060389
• blood vessel remodeling
  http://purl.obolibrary.org/obo/GO_0001974
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• positive regulation of integrin biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045726
• positive regulation of epithelial cell migration
  http://purl.obolibrary.org/obo/GO_0010634
• somatic stem cell division
  http://purl.obolibrary.org/obo/GO_0048103
• cell migration
  http://purl.obolibrary.org/obo/GO_0016477
• cardioblast differentiation
  http://purl.obolibrary.org/obo/GO_0010002
• receptor signaling protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004702
• axon guidance
  http://purl.obolibrary.org/obo/GO_0007411
• positive regulation of cell division
  http://purl.obolibrary.org/obo/GO_0051781
• response to hypoxia
  http://purl.obolibrary.org/obo/GO_0001666
• hemopoiesis
  http://purl.obolibrary.org/obo/GO_0030097
• glial cell migration
  http://purl.obolibrary.org/obo/GO_0008347
• hair follicle morphogenesis
  http://purl.obolibrary.org/obo/GO_0031069
• positive regulation of cell growth
  http://purl.obolibrary.org/obo/GO_0030307
• catagen
  http://purl.obolibrary.org/obo/GO_0042637
• negative regulation of keratinocyte differentiation
  http://purl.obolibrary.org/obo/GO_0045617
• cell death
  http://purl.obolibrary.org/obo/GO_0008219
• extracellular matrix organization
  http://purl.obolibrary.org/obo/GO_0030198
• axon
  http://purl.obolibrary.org/obo/GO_0030424
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• transforming growth factor beta receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007179
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• basement membrane
  http://purl.obolibrary.org/obo/GO_0005604
• protein N-terminus binding
  http://purl.obolibrary.org/obo/GO_0047485
• response to estrogen
  http://purl.obolibrary.org/obo/GO_0043627
• cell growth
  http://purl.obolibrary.org/obo/GO_0016049
• blood vessel development
  http://purl.obolibrary.org/obo/GO_0001568
• activation-induced cell death of T cells
  http://purl.obolibrary.org/obo/GO_0006924
• cell cycle arrest
  http://purl.obolibrary.org/obo/GO_0007050
• positive regulation of cell cycle
  http://purl.obolibrary.org/obo/GO_0045787
• cardiac right ventricle morphogenesis
  http://purl.obolibrary.org/obo/GO_0003215
• collagen fibril organization
  http://purl.obolibrary.org/obo/GO_0030199
• transforming growth factor beta receptor binding
  http://purl.obolibrary.org/obo/GO_0005160
• positive regulation of stress-activated MAPK cascade
  http://purl.obolibrary.org/obo/GO_0032874
• secretory granule
  http://purl.obolibrary.org/obo/GO_0030141
• embryonic neurocranium morphogenesis
  http://purl.obolibrary.org/obo/GO_0048702
• regulation of SMAD protein import into nucleus
  http://purl.obolibrary.org/obo/GO_0060390
• negative regulation of epithelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0050680
• negative regulation of release of sequestered calcium ion into cytosol
  http://purl.obolibrary.org/obo/GO_0051280
• activation of protein kinase activity
  http://purl.obolibrary.org/obo/GO_0032147
• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• cardiac epithelial to mesenchymal transition
  http://purl.obolibrary.org/obo/GO_0060317
• neuronal cell body
  http://purl.obolibrary.org/obo/GO_0043025
• cartilage condensation
  http://purl.obolibrary.org/obo/GO_0001502
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• positive regulation of protein secretion
  http://purl.obolibrary.org/obo/GO_0050714
• positive regulation of catagen
  http://purl.obolibrary.org/obo/GO_0051795
• negative regulation of alkaline phosphatase activity
  http://purl.obolibrary.org/obo/GO_0010693
• positive regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030335
• outflow tract morphogenesis
  http://purl.obolibrary.org/obo/GO_0003151
• dopamine biosynthetic process
  http://purl.obolibrary.org/obo/GO_0042416
• heart development
  http://purl.obolibrary.org/obo/GO_0007507
• positive regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010628
• type II transforming growth factor beta receptor binding
  http://purl.obolibrary.org/obo/GO_0005114
• cell-cell junction organization
  http://purl.obolibrary.org/obo/GO_0045216
• growth factor activity
  http://purl.obolibrary.org/obo/GO_0008083
• cardiac left ventricle morphogenesis
  http://purl.obolibrary.org/obo/GO_0003214
• negative regulation of cell growth
  http://purl.obolibrary.org/obo/GO_0030308
• positive regulation of cardioblast differentiation
  http://purl.obolibrary.org/obo/GO_0051891
• protein heterodimerization activity
  http://purl.obolibrary.org/obo/GO_0046982
• positive regulation of cell adhesion mediated by integrin
  http://purl.obolibrary.org/obo/GO_0033630

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05410
• http://www.genome.jp/dbget-bin/www_bget?map05152
• http://www.genome.jp/dbget-bin/www_bget?map05220
• http://www.genome.jp/dbget-bin/www_bget?map05210
• http://www.genome.jp/dbget-bin/www_bget?map04350
• http://www.genome.jp/dbget-bin/www_bget?map05140
• http://www.genome.jp/dbget-bin/www_bget?map05211
• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map04010
• http://www.genome.jp/dbget-bin/www_bget?map05142
• http://www.genome.jp/dbget-bin/www_bget?map04380
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05145
• http://www.genome.jp/dbget-bin/www_bget?map05212
• http://www.genome.jp/dbget-bin/www_bget?map04144
• http://www.genome.jp/dbget-bin/www_bget?map05146
• http://www.genome.jp/dbget-bin/www_bget?map05144
• http://www.genome.jp/dbget-bin/www_bget?map05414
• http://www.genome.jp/dbget-bin/www_bget?map04110
• http://www.genome.jp/dbget-bin/www_bget?map05323
• http://www.genome.jp/dbget-bin/www_bget?map04060

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Osteoclast differentiation
• Pancreatic cancer
• Renal cell carcinoma
• Pathways in cancer
• Chronic myeloid leukemia
• Amoebiasis
• Malaria
• Rheumatoid arthritis
• Tuberculosis
• Toxoplasmosis
• Dilated cardiomyopathy
• Chagas disease (American trypanosomiasis)
• Cytokine-cytokine receptor interaction
• Hypertrophic cardiomyopathy (HCM)
• MAPK signaling pathway
• TGF-beta signaling pathway
• Colorectal cancer
• Leishmaniasis
• Cell cycle
• HTLV-I infection
• Endocytosis