CD12894

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12894

CD12894

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Lamb1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• laminin B1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• laminin-10 subunit beta
• laminin-1 subunit beta
• laminin B1 chain
• laminin-12 subunit beta
• laminin B1
• laminin-8 subunit beta
• laminin B1 subunit 1
• laminin subunit beta-1
• laminin-6 subunit beta
• laminin-2 subunit beta

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Lamb-1
• Lamb1-1
• C77966
• C80098
• C81607
• D130003D08Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16777

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• laminin B1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96743

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008482

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000002900

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.172674

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=150240

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Aldrin E. Molero, et.al., Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19955426
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• R. Okano, et.al., Characterization of a novel promoter structure and its transcriptional regulation of the murine laminin B1 gene., Biochimica et biophysica acta, 1992, 1132
  http://rdf.ncbi.nlm.nih.gov/pubmed/1339296
• Yujin. Zhang, et.al., Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea., Journal of cell science, 2010, 123
  http://rdf.ncbi.nlm.nih.gov/pubmed/20332116
• L. Schuger, et.al., Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development., Developmental biology, 1991, 146
  http://rdf.ncbi.nlm.nih.gov/pubmed/1907584
• K B. Avraham, et.al., Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3 alpha, HNF-3 beta, HNF-3 gamma, and HNF-4., Genomics, 1992, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/1612587
• Stefan. Kalkhof, et.al., Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking., Proteins, 2010, 78
  http://rdf.ncbi.nlm.nih.gov/pubmed/20939100
• L J. Dong, et.al., The expression of the genes for entactin, laminin A, laminin B1 and laminin B2 in murine lens morphogenesis and eye development., Differentiation; research in biological diversity, 1991, 48
  http://rdf.ncbi.nlm.nih.gov/pubmed/1725162
• Stefan. Kalkhof, et.al., A novel disulfide pattern in laminin-type epidermal growth factor-like (LE) modules of laminin β1 and γ1 chains., Biochemistry, 2010, 49
  http://rdf.ncbi.nlm.nih.gov/pubmed/20731416
• L. Schuger, et.al., Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells., Developmental dynamics : an official publication of the American Association of Anatomists, 1992, 195
  http://rdf.ncbi.nlm.nih.gov/pubmed/1292752

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• negative regulation of cell adhesion
  http://purl.obolibrary.org/obo/GO_0007162
• cell adhesion
  http://purl.obolibrary.org/obo/GO_0007155
• learning or memory
  http://purl.obolibrary.org/obo/GO_0007611
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• laminin-8 complex
  http://purl.obolibrary.org/obo/GO_0043257
• laminin-2 complex
  http://purl.obolibrary.org/obo/GO_0005607
• positive regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030335
• embryo implantation
  http://purl.obolibrary.org/obo/GO_0007566
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• integrin binding
  http://purl.obolibrary.org/obo/GO_0005178
• laminin-1 complex
  http://purl.obolibrary.org/obo/GO_0005606
• odontogenesis
  http://purl.obolibrary.org/obo/GO_0042476
• enzyme binding
  http://purl.obolibrary.org/obo/GO_0019899
• laminin-10 complex
  http://purl.obolibrary.org/obo/GO_0043259
• glycosphingolipid binding
  http://purl.obolibrary.org/obo/GO_0043208
• cell migration
  http://purl.obolibrary.org/obo/GO_0016477
• extracellular matrix structural constituent
  http://purl.obolibrary.org/obo/GO_0005201
• proteinaceous extracellular matrix
  http://purl.obolibrary.org/obo/GO_0005578
• extracellular matrix
  http://purl.obolibrary.org/obo/GO_0031012
• substrate adhesion-dependent cell spreading
  http://purl.obolibrary.org/obo/GO_0034446
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• laminin complex
  http://purl.obolibrary.org/obo/GO_0043256
• basement membrane
  http://purl.obolibrary.org/obo/GO_0005604
• neuron projection development
  http://purl.obolibrary.org/obo/GO_0031175
• basal lamina
  http://purl.obolibrary.org/obo/GO_0005605
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04510
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05145
• http://www.genome.jp/dbget-bin/www_bget?map05146
• http://www.genome.jp/dbget-bin/www_bget?map04512
• http://www.genome.jp/dbget-bin/www_bget?map05222

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Small cell lung cancer
• Pathways in cancer
• Focal adhesion
• Toxoplasmosis
• Amoebiasis
• ECM-receptor interaction