CD13175

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13175

CD13175

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• P4ha1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• prolyl 4-hydroxylase subunit alpha-1
• procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
• procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1
• 4-PH alpha-1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• P4ha
• AL022634

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18451

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:97463

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011030

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000019916

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2212

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=176710

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Tiina. Holster, et.al., Loss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null mice., The Journal of biological chemistry, 2007, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/17135260
• T. Helaakoski, et.al., Increases in mRNA concentrations of the alpha and beta subunits of prolyl 4-hydroxylase accompany increased gene expression of type IV collagen during differentiation of mouse F9 cells., The Journal of biological chemistry, 1990, 265
  http://rdf.ncbi.nlm.nih.gov/pubmed/1694844
• T. Helaakoski, et.al., Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7753822
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821
• Ewa. Wandzioch, et.al., Lhx2-/- mice develop liver fibrosis., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/15536133
• Michael S. Rogers, et.al., Genetic loci that control vascular endothelial growth factor-induced angiogenesis., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12958152

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• peptidyl-proline hydroxylation to 4-hydroxy-L-proline
  http://purl.obolibrary.org/obo/GO_0018401
• collagen fibril organization
  http://purl.obolibrary.org/obo/GO_0030199
• intracellular membrane-bounded organelle
  http://purl.obolibrary.org/obo/GO_0043231
• procollagen-proline 4-dioxygenase activity
  http://purl.obolibrary.org/obo/GO_0004656
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
  http://purl.obolibrary.org/obo/GO_0016706
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• binding
  http://purl.obolibrary.org/obo/GO_0005488
• iron ion binding
  http://purl.obolibrary.org/obo/GO_0005506
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• L-ascorbic acid binding
  http://purl.obolibrary.org/obo/GO_0031418
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
  http://purl.obolibrary.org/obo/GO_0016702
• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  http://purl.obolibrary.org/obo/GO_0016705

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00330
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Arginine and proline metabolism
• Metabolic pathways