CD13209

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13209

CD13209

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Srebf2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• sterol regulatory element binding factor 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• sterol regulatory element-binding protein 2
• sterol regulatory element binding factor 2
• sterol regulatory element-binding transcription factor 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• nuc
• SREBP-2
• SREBP2gc
• SREBP2
• lop13
• AI608257
• bHLHd2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20788

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• sterol regulatory element binding factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:107585

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_033218

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022463

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.38016

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600481

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• S. Myöhänen, et.al., Nucleotide sequence of mouse spermidine synthase cDNA., DNA sequence : the journal of DNA sequencing and mapping, 1994, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/7803821
• Isabelle. Gerin, et.al., Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20732877
• Shin-ichi. Inoue, et.al., Activated sterol regulatory element-binding protein-2 suppresses hepatocyte nuclear factor-4-mediated Cyp3a11 expression in mouse liver., Molecular pharmacology, 2011, 79
  http://rdf.ncbi.nlm.nih.gov/pubmed/20926756
• H. Shimano, et.al., Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a., The Journal of clinical investigation, 1996, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/8833906
• Ryo. Suzuki, et.al., Diabetes and insulin in regulation of brain cholesterol metabolism., Cell metabolism, 2010, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/21109190
• Tyler J. Marquart, et.al., miR-33 links SREBP-2 induction to repression of sterol transporters., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20566875
• C L. Welch, et.al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes., Journal of lipid research, 1996, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/8827514
• M. Klingenspor, et.al., Localization of profilin-1 (Pfn1) and a related sequence (Pfn1-rs) to mouse chromosomes 11 and 15 respectively., Mammalian genome : official journal of the International Mammalian Genome Society, 1997, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/9196007
• Sabrina. Bauer, et.al., Sterol regulatory element-binding protein 2 (SREBP2) activation after excess triglyceride storage induces chemerin in hypertrophic adipocytes., Endocrinology, 2011, 152
  http://rdf.ncbi.nlm.nih.gov/pubmed/21084441
• L. Kauppinen, et.al., Transgenic mice over-expressing the human spermidine synthase gene., The Biochemical journal, 1993, 293 ( Pt 2)
  http://rdf.ncbi.nlm.nih.gov/pubmed/8343131

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• SREBP-SCAP-Insig complex
  http://purl.obolibrary.org/obo/GO_0032937
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• SREBP signaling pathway
  http://purl.obolibrary.org/obo/GO_0032933
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• chromatin binding
  http://purl.obolibrary.org/obo/GO_0003682
• response to hormone
  http://purl.obolibrary.org/obo/GO_0009725
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• steroid metabolic process
  http://purl.obolibrary.org/obo/GO_0008202
• cytoplasmic vesicle
  http://purl.obolibrary.org/obo/GO_0031410
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• lipid metabolic process
  http://purl.obolibrary.org/obo/GO_0006629
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• cholesterol metabolic process
  http://purl.obolibrary.org/obo/GO_0008203
• protein C-terminus binding
  http://purl.obolibrary.org/obo/GO_0008022
• dendrite
  http://purl.obolibrary.org/obo/GO_0030425

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName