CD13511

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13511

CD13511

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Uaca

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• uveal autoantigen with coiled-coil domains and ankyrin repeats

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• uveal autoantigen with coiled-coil domains and ankyrin repeats
• nuclear membrane binding protein NUCLING
• nuclear membrane-binding protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 2700059D02Rik
• nucling

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/72565

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• uveal autoantigen with coiled-coil domains and ankyrin repeats
  http://metadb.riken.jp/db/mgi_rdf/MGI:1919815

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_028283

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000034485

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.68819

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=612516

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Ayano. Kawaguchi, et.al., Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis., Development (Cambridge, England), 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/18725516
• Li. Liu, et.al., Nucling interacts with nuclear factor-kappaB, regulating its cellular distribution., The FEBS journal, 2009, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/19187222
• Xichuan. Teng, et.al., Attenuation of MPTP-induced neurotoxicity and locomotor dysfunction in Nucling-deficient mice via suppression of the apoptosome pathway., Journal of neurochemistry, 2006, 97
  http://rdf.ncbi.nlm.nih.gov/pubmed/16686692
• Li. Liu, et.al., Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling., The Biochemical journal, 2004, 380
  http://rdf.ncbi.nlm.nih.gov/pubmed/14961764
• Takashi. Sakai, et.al., Inflammatory disease and cancer with a decrease in Kupffer cell numbers in Nucling-knockout mice., International journal of cancer, 2010, 126
  http://rdf.ncbi.nlm.nih.gov/pubmed/19637241
• Takashi. Sakai, et.al., Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15271982
• Noriko. Okazaki, et.al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries., DNA research : an international journal for rapid publication of reports on genes and genomes, 2004, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/15368895
• Takashi. Sakai, et.al., Identification of a novel, embryonal carcinoma cell-associated molecule, nucling, that is up-regulated during cardiac muscle differentiation., Journal of biochemistry, 2003, 133
  http://rdf.ncbi.nlm.nih.gov/pubmed/12761289
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Nam Hoang. Tran, et.al., NF-kappaB regulates the expression of Nucling, a novel apoptosis regulator, with involvement of proteasome and caspase for its degradation., Journal of biochemistry, 2010, 148
  http://rdf.ncbi.nlm.nih.gov/pubmed/20702393

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• intrinsic apoptotic signaling pathway in response to oxidative stress
  http://purl.obolibrary.org/obo/GO_0008631
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• negative regulation of inflammatory response
  http://purl.obolibrary.org/obo/GO_0050728
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• apoptosome
  http://purl.obolibrary.org/obo/GO_0043293
• response to UV
  http://purl.obolibrary.org/obo/GO_0009411
• nuclear envelope
  http://purl.obolibrary.org/obo/GO_0005635
• negative regulation of NIK/NF-kappaB signaling
  http://purl.obolibrary.org/obo/GO_1901223
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0043280
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• positive regulation of protein import into nucleus
  http://purl.obolibrary.org/obo/GO_0042307
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• intrinsic apoptotic signaling pathway in response to DNA damage
  http://purl.obolibrary.org/obo/GO_0008630

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName