CD13826

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13826

CD13826

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rxra

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• retinoid X receptor alpha

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• retinoid X receptor alpha
• retinoic acid receptor RXR-alpha
• nuclear receptor subfamily 2 group B member 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• RXR alpha 1
• RXRalpha1
• Nr2b1
• 9530071D11Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20181

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• retinoid X receptor alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:98214

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011305

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000015846

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.24624

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=180245

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• B. Le Douarin, et.al., The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18., The EMBO journal, 1995, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/7744009
• D J. Mangelsdorf, et.al., Characterization of three RXR genes that mediate the action of 9-cis retinoic acid., Genes & development, 1992, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/1312497
• Zhixing. Wang, et.al., RXRα ablation in epidermal keratinocytes enhances UVR-induced DNA damage, apoptosis, and proliferation of keratinocytes and melanocytes., The Journal of investigative dermatology, 2011, 131
  http://rdf.ncbi.nlm.nih.gov/pubmed/20944655
• M. Leid, et.al., Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently., Cell, 1992, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/1310259
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• E. Dyson, et.al., Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7638202
• Tamás. Roszer, et.al., Autoimmune kidney disease and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha deficiency., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21135166
• C W. Hoopes, et.al., Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma., Genomics, 1992, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/1358808
• Thomas. Brade, et.al., Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2., Development (Cambridge, England), 2011, 138
  http://rdf.ncbi.nlm.nih.gov/pubmed/21138976
• Richard. Daneman, et.al., The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/21060791

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• peroxisome proliferator activated receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0035357
• regulation of branching involved in prostate gland morphogenesis
  http://purl.obolibrary.org/obo/GO_0060687
• visceral serous pericardium development
  http://purl.obolibrary.org/obo/GO_0061032
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• negative regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010629
• response to glucocorticoid
  http://purl.obolibrary.org/obo/GO_0051384
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• enzyme binding
  http://purl.obolibrary.org/obo/GO_0019899
• heart development
  http://purl.obolibrary.org/obo/GO_0007507
• angiogenesis involved in coronary vascular morphogenesis
  http://purl.obolibrary.org/obo/GO_0060978
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• 9-cis retinoic acid receptor activity
  http://purl.obolibrary.org/obo/GO_0004886
• steroid hormone receptor activity
  http://purl.obolibrary.org/obo/GO_0003707
• ventricular cardiac muscle tissue morphogenesis
  http://purl.obolibrary.org/obo/GO_0055010
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• steroid hormone mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0043401
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
  http://purl.obolibrary.org/obo/GO_0060528
• double-stranded DNA binding
  http://purl.obolibrary.org/obo/GO_0003690
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
  http://purl.obolibrary.org/obo/GO_0004879
• protein heterodimerization activity
  http://purl.obolibrary.org/obo/GO_0046982
• mesenchyme development
  http://purl.obolibrary.org/obo/GO_0060485
• retinoic acid-responsive element binding
  http://purl.obolibrary.org/obo/GO_0044323
• cardiac muscle cell differentiation
  http://purl.obolibrary.org/obo/GO_0055007
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• modulation by virus of host morphology or physiology
  http://purl.obolibrary.org/obo/GO_0019048
• cardiac muscle cell proliferation
  http://purl.obolibrary.org/obo/GO_0060038
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• heart morphogenesis
  http://purl.obolibrary.org/obo/GO_0003007
• steroid binding
  http://purl.obolibrary.org/obo/GO_0005496
• axon
  http://purl.obolibrary.org/obo/GO_0030424
• ventricular cardiac muscle cell differentiation
  http://purl.obolibrary.org/obo/GO_0055012
• retinoic acid receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0048384
• response to retinoic acid
  http://purl.obolibrary.org/obo/GO_0032526
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• vitamin D receptor binding
  http://purl.obolibrary.org/obo/GO_0042809
• nuclear chromatin
  http://purl.obolibrary.org/obo/GO_0000790
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04976
• http://www.genome.jp/dbget-bin/www_bget?map05222
• http://www.genome.jp/dbget-bin/www_bget?map05216
• http://www.genome.jp/dbget-bin/www_bget?map05223
• http://www.genome.jp/dbget-bin/www_bget?map05202
• http://www.genome.jp/dbget-bin/www_bget?map04920
• http://www.genome.jp/dbget-bin/www_bget?map03320
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05160

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• PPAR signaling pathway
• Transcriptional misregulation in cancers
• Small cell lung cancer
• Thyroid cancer
• Non-small cell lung cancer
• Pathways in cancer
• Bile secretion
• Hepatitis C
• Adipocytokine signaling pathway