CD13938

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13938

CD13938

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Gabbr1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• gamma-aminobutyric acid (GABA) B receptor, 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• gamma-aminobutyric acid (GABA-B) receptor, 1
• GABA-B-R1
• GABA-BR1b receptor
• GABA-BR1
• gamma-aminobutyric acid type B receptor subunit 1
• bM573K1.1.1 (gamma-aminobutyric acid (GABA) B receptor, 1a)
• GABA-B receptor 1
• gamma-aminobutyric acid (GABA) B receptor, 1
• gb1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• GABAB1
• bM573K1.1
• GABAbR1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/54393

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• gamma-aminobutyric acid (GABA) B receptor, 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1860139

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_019439

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024462

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.32191

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603540

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• R. Sullivan, et.al., Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor., The Journal of pharmacology and experimental therapeutics, 2000, 293
  http://rdf.ncbi.nlm.nih.gov/pubmed/10773016
• R. Kuner, et.al., Role of heteromer formation in GABAB receptor function., Science (New York, N.Y.), 1999, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/9872744
• H M. Prosser, et.al., Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice., Molecular and cellular neurosciences, 2001, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/11414794
• Julie. Vienne, et.al., Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20962240
• Tudor. Bartoi, et.al., GABAB receptor constituents revealed by tandem affinity purification from transgenic mice., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20406808
• Yu. Fu, et.al., Differential dynamics and activity-dependent regulation of alpha- and beta-neurexins at developing GABAergic synapses., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/21149722
• K. Lamp, et.al., The murine GABA(B) receptor 1: cDNA cloning, tissue distribution, structure of the Gabbr1 gene, and mapping to chromosome 17., Cytogenetics and cell genetics, 2001, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/11306808
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• F. Calon, et.al., Effect of MPTP-induced denervation on basal ganglia GABA(B) receptors: correlation with dopamine concentrations and dopamine transporter., Synapse (New York, N.Y.), 2001, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/11304760
• Nicole. Guetg, et.al., NMDA receptor-dependent GABAB receptor internalization via CaMKII phosphorylation of serine 867 in GABAB1., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20643921

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• negative regulation of epinephrine secretion
  http://purl.obolibrary.org/obo/GO_0032811
• negative regulation of adenylate cyclase activity
  http://purl.obolibrary.org/obo/GO_0007194
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• regulation of glutamate secretion
  http://purl.obolibrary.org/obo/GO_0014048
• mitochondrial membrane
  http://purl.obolibrary.org/obo/GO_0031966
• negative regulation of dopamine secretion
  http://purl.obolibrary.org/obo/GO_0033602
• endoplasmic reticulum membrane
  http://purl.obolibrary.org/obo/GO_0005789
• neuronal cell body
  http://purl.obolibrary.org/obo/GO_0043025
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• G-protein coupled receptor activity
  http://purl.obolibrary.org/obo/GO_0004930
• negative regulation of gamma-aminobutyric acid secretion
  http://purl.obolibrary.org/obo/GO_0014053
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• axolemma
  http://purl.obolibrary.org/obo/GO_0030673
• synaptosome
  http://purl.obolibrary.org/obo/GO_0019717
• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• G-protein coupled GABA receptor activity
  http://purl.obolibrary.org/obo/GO_0004965
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• dendritic spine
  http://purl.obolibrary.org/obo/GO_0043197
• positive regulation of growth hormone secretion
  http://purl.obolibrary.org/obo/GO_0060124
• regulation of cAMP biosynthetic process
  http://purl.obolibrary.org/obo/GO_0030817
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• osteoblast differentiation
  http://purl.obolibrary.org/obo/GO_0001649
• negative regulation of synaptic transmission
  http://purl.obolibrary.org/obo/GO_0050805
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• transcription factor binding
  http://purl.obolibrary.org/obo/GO_0008134
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• postsynaptic membrane
  http://purl.obolibrary.org/obo/GO_0045211
• synaptic vesicle
  http://purl.obolibrary.org/obo/GO_0008021
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• dendritic shaft
  http://purl.obolibrary.org/obo/GO_0043198
• synapse
  http://purl.obolibrary.org/obo/GO_0045202

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04727
• http://www.genome.jp/dbget-bin/www_bget?map04080

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Neuroactive ligand-receptor interaction
• GABAergic synapse