CD14233

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD14233

CD14233

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ddr2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• discoidin domain receptor family, member 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• discoidin domain receptor family, member 2
• discoidin domain-containing receptor 2
• tyrosine-protein kinase TYRO10
• CD167 antigen-like family member B
• receptor protein-tyrosine kinase TKT
• neurotrophic tyrosine kinase, receptor-related 3
• discoidin domain receptor 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Ntrkr3
• tyro10
• AW495251

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18214

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• discoidin domain receptor family, member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1345277

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_022563

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000026674

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.229249

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=191311

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Maryna. Baydyuk, et.al., TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21205893
• Lisa A. Flynn, et.al., Inhibition of collagen fibrillogenesis by cells expressing soluble extracellular domains of DDR1 and DDR2., Journal of molecular biology, 2010, 395
  http://rdf.ncbi.nlm.nih.gov/pubmed/19900459
• C. Lai, et.al., Structure and expression of the Tyro 10 receptor tyrosine kinase., Oncogene, 1994, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/8108131
• Lin. Xu, et.al., Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice., Arthritis and rheumatism, 2010, 62
  http://rdf.ncbi.nlm.nih.gov/pubmed/20518074
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• T. Karn, et.al., Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain., Oncogene, 1993, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/8247548
• Lalitha. Sivakumar, et.al., The influence of discoidin domain receptor 2 on the persistence length of collagen type I fibers., Biomaterials, 2010, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/20346496
• C. Lai, et.al., An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system., Neuron, 1991, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/2025425
• C L. Sommers, et.al., Murine txk: a protein tyrosine kinase gene regulated by T cell activation., Oncogene, 1995, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/7542761
• S. Edelhoff, et.al., Mapping of the receptor protein-tyrosine kinase 10 to human chromosome 1q21-q23 and mouse chromosome 1H1-5 by fluorescence in situ hybridization., Genomics, 1995, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/7774952

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0046777
• positive regulation of cell cycle arrest
  http://purl.obolibrary.org/obo/GO_0071158
• peptidyl-tyrosine phosphorylation
  http://purl.obolibrary.org/obo/GO_0018108
• transmembrane receptor protein tyrosine kinase signaling pathway
  http://purl.obolibrary.org/obo/GO_0007169
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• positive regulation of sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0051091
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• positive regulation of fibroblast proliferation
  http://purl.obolibrary.org/obo/GO_0048146
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• regulation of bone mineralization
  http://purl.obolibrary.org/obo/GO_0030500
• ossification
  http://purl.obolibrary.org/obo/GO_0001503
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• apical plasma membrane
  http://purl.obolibrary.org/obo/GO_0016324
• transmembrane receptor protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0004714
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• positive regulation of osteoblast differentiation
  http://purl.obolibrary.org/obo/GO_0045669
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• cell adhesion
  http://purl.obolibrary.org/obo/GO_0007155
• protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0004713
• collagen binding
  http://purl.obolibrary.org/obo/GO_0005518
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• positive regulation of protein kinase activity
  http://purl.obolibrary.org/obo/GO_0045860
• positive regulation of fibroblast migration
  http://purl.obolibrary.org/obo/GO_0010763

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName