CD14293

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD14293

CD14293

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pak7

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• p21 protein (Cdc42/Rac)-activated kinase 7

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• p21 protein (Cdc42/Rac)-activated kinase 7
• p21-activated kinase 5
• PAK-5
• serine/threonine-protein kinase PAK 7
• p21-activated kinase 7
• PAK-7

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 2900083L08Rik
• 6430627N20
• Pak5

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/241656

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• p21 protein (Cdc42/Rac)-activated kinase 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920334

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_172858

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000039913

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.131572

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=608038

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Rosanna Pescini. Gobert, et.al., Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits., Molecular and cellular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19139271
• Xiaofan. Li, et.al., Targeted disruption of the gene for the PAK5 kinase in mice., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/14517284
• David J. Pagliarini, et.al., A mitochondrial protein compendium elucidates complex I disease biology., Cell, 2008, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/18614015
• Sophie. Cotteret, et.al., p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12897128
• Tanya. Nekrasova, et.al., Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion., Developmental biology, 2008, 322
  http://rdf.ncbi.nlm.nih.gov/pubmed/18675265
• Tamar. Sapir, et.al., Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18509032
• Monika. Niehof, et.al., RSK4 and PAK5 are novel candidate genes in diabetic rat kidney and brain., Molecular pharmacology, 2005, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/15615695
• Jonathan C. Trinidad, et.al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations., Molecular & cellular proteomics : MCP, 2006, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/16452087

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04510
• http://www.genome.jp/dbget-bin/www_bget?map04660
• http://www.genome.jp/dbget-bin/www_bget?map04360
• http://www.genome.jp/dbget-bin/www_bget?map05211
• http://www.genome.jp/dbget-bin/www_bget?map04012
• http://www.genome.jp/dbget-bin/www_bget?map04810

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• T cell receptor signaling pathway
• Axon guidance
• Regulation of actin cytoskeleton
• Focal adhesion
• Renal cell carcinoma
• ErbB signaling pathway