CD14751

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD14751

CD14751

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Crh

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• corticotropin releasing hormone

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• corticotropin releasing hormone
• corticotropin-releasing hormone
• corticoliberin

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• corticotropin releasing factor
• corticotropin-releasing factor
• Gm1347
• LOC383938
• CRF

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12918

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• corticotropin releasing hormone
  http://metadb.riken.jp/db/mgi_rdf/MGI:88496

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_205769

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000049796

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.290689

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=122560

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Yoshinori. Sato, et.al., The role of endogenous glucocorticoids in lymphocyte development in melanocortin receptor 2-deficient mice., Biochemical and biophysical research communications, 2010, 403
  http://rdf.ncbi.nlm.nih.gov/pubmed/21056545
• Evan. Elliott, et.al., Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice., Nature neuroscience, 2010, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890295
• G F. Koob, et.al., Corticotropin-releasing factor and behavior., Federation proceedings, 1985, 44
  http://rdf.ncbi.nlm.nih.gov/pubmed/3871412
• C E. Keegan, et.al., Expression of corticotropin-releasing hormone transgenes in neurons of adult and developing mice., Molecular and cellular neurosciences, 1994, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/7704423
• Marc. Simard, et.al., Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation., Reproductive biology and endocrinology : RB&E, 2010, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/21050473
• Mina. Delawary, et.al., NMDAR2B tyrosine phosphorylation regulates anxiety-like behavior and CRF expression in the amygdala., Molecular brain, 2010, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/21118530
• Zoi. Chaniotou, et.al., Corticotropin-releasing factor regulates TLR4 expression in the colon and protects mice from colitis., Gastroenterology, 2010, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/20732324
• M R. Brown, et.al., Corticotropin-releasing factor: effects on the autonomic nervous system and visceral systems., Federation proceedings, 1985, 44
  http://rdf.ncbi.nlm.nih.gov/pubmed/2981744
• W. Vale, et.al., Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin., Science (New York, N.Y.), 1981, 213
  http://rdf.ncbi.nlm.nih.gov/pubmed/6267699
• L. Muglia, et.al., Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need., Nature, 1995, 373
  http://rdf.ncbi.nlm.nih.gov/pubmed/7830793

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• response to stress
  http://purl.obolibrary.org/obo/GO_0006950
• negative regulation of norepinephrine secretion
  http://purl.obolibrary.org/obo/GO_0010700
• glucocorticoid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006704
• corticotropin-releasing hormone receptor 2 binding
  http://purl.obolibrary.org/obo/GO_0051431
• negative regulation of blood pressure
  http://purl.obolibrary.org/obo/GO_0045776
• negative regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010629
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• negative regulation of epinephrine secretion
  http://purl.obolibrary.org/obo/GO_0032811
• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• positive regulation of protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0001934
• varicosity
  http://purl.obolibrary.org/obo/GO_0043196
• regulation of serotonin secretion
  http://purl.obolibrary.org/obo/GO_0014062
• negative regulation of glucagon secretion
  http://purl.obolibrary.org/obo/GO_0070093
• positive regulation of digestive system process
  http://purl.obolibrary.org/obo/GO_0060456
• feeding behavior
  http://purl.obolibrary.org/obo/GO_0007631
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• negative regulation of cell death
  http://purl.obolibrary.org/obo/GO_0060548
• hormone activity
  http://purl.obolibrary.org/obo/GO_0005179
• hormone-mediated apoptotic signaling pathway
  http://purl.obolibrary.org/obo/GO_0008628
• corticotropin-releasing hormone receptor 1 binding
  http://purl.obolibrary.org/obo/GO_0051430
• learning or memory
  http://purl.obolibrary.org/obo/GO_0007611
• positive regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010628
• positive regulation of cAMP biosynthetic process
  http://purl.obolibrary.org/obo/GO_0030819
• positive regulation of cortisol secretion
  http://purl.obolibrary.org/obo/GO_0051464
• positive regulation of cell death
  http://purl.obolibrary.org/obo/GO_0010942
• positive regulation of corticotropin secretion
  http://purl.obolibrary.org/obo/GO_0051461
• locomotory exploration behavior
  http://purl.obolibrary.org/obo/GO_0035641
• adrenal gland development
  http://purl.obolibrary.org/obo/GO_0030325
• perikaryon
  http://purl.obolibrary.org/obo/GO_0043204
• positive regulation of corticosterone secretion
  http://purl.obolibrary.org/obo/GO_2000854
• inflammatory response
  http://purl.obolibrary.org/obo/GO_0006954
• neuroprotection
  http://purl.obolibrary.org/obo/GO_0043526
• positive regulation of insulin secretion involved in cellular response to glucose stimulus
  http://purl.obolibrary.org/obo/GO_0035774
• long-term memory
  http://purl.obolibrary.org/obo/GO_0007616
• positive regulation of behavioral fear response
  http://purl.obolibrary.org/obo/GO_2000987
• corticotropin-releasing hormone activity
  http://purl.obolibrary.org/obo/GO_0017045
• negative regulation of luteinizing hormone secretion
  http://purl.obolibrary.org/obo/GO_0033685
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• positive regulation of calcium ion import
  http://purl.obolibrary.org/obo/GO_0090280
• neuronal cell body
  http://purl.obolibrary.org/obo/GO_0043025
• lung development
  http://purl.obolibrary.org/obo/GO_0030324
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• associative learning
  http://purl.obolibrary.org/obo/GO_0008306

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04080
• http://www.genome.jp/dbget-bin/www_bget?map04730

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Neuroactive ligand-receptor interaction
• Long-term depression