CD15072

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15072

CD15072

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Fpgs

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• folylpolyglutamyl synthetase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• folylpoly-gamma-glutamate synthetase
• folylpolyglutamyl synthetase
• tetrahydrofolylpolyglutamate synthase
• folylpolyglutamate synthase, mitochondrial
• tetrahydrofolate synthase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AA408187

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/14287

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• folylpolyglutamyl synthetase
  http://metadb.riken.jp/db/mgi_rdf/MGI:95576

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010236

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000009566

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.3830

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=136510

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• G. Levan, et.al., The gene map of the Norway rat (Rattus norvegicus) and comparative mapping with mouse and man., Genomics, 1991, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/1889815
• Alexandra C. Racanelli, et.al., A mouse gene that coordinates epigenetic controls and transcriptional interference to achieve tissue-specific expression., Molecular and cellular biology, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/17998333
• David L. Delano, et.al., Genetically based resistance to the antiinflammatory effects of methotrexate in the air-pouch model of acute inflammation., Arthritis and rheumatism, 2005, 52
  http://rdf.ncbi.nlm.nih.gov/pubmed/16059892
• L B. Rowe, et.al., Maps from two interspecific backcross DNA panels available as a community genetic mapping resource., Mammalian genome : official journal of the International Mammalian Genome Society, 1994, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/8075499
• David J. Pagliarini, et.al., A mitochondrial protein compendium elucidates complex I disease biology., Cell, 2008, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/18614015
• R E. Fournier, et.al., Complementation mapping in microcell hybrids: localization of Fpgs and Ak-1 on Mus musculus chromosome 2., Somatic cell genetics, 1983, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/6687641
• A. Pilz, et.al., Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse., Genomics, 1995, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/7774911
• Etsuko. Sakamoto, et.al., Folylpolyglutamate synthase and gamma-glutamyl hydrolase regulate leucovorin-enhanced 5-fluorouracil anticancer activity., Biochemical and biophysical research communications, 2008, 365
  http://rdf.ncbi.nlm.nih.gov/pubmed/18035049
• K. Roy, et.al., Different antifolate-resistant L1210 cell variants with either increased or decreased folylpolyglutamate synthetase gene expression at the level of mRNA transcription., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7592937

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• one-carbon metabolic process
  http://purl.obolibrary.org/obo/GO_0006730
• ligase activity
  http://purl.obolibrary.org/obo/GO_0016874
• biosynthetic process
  http://purl.obolibrary.org/obo/GO_0009058
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• tetrahydrofolylpolyglutamate biosynthetic process
  http://purl.obolibrary.org/obo/GO_0046901
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• folic acid-containing compound biosynthetic process
  http://purl.obolibrary.org/obo/GO_0009396
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• tetrahydrofolylpolyglutamate synthase activity
  http://purl.obolibrary.org/obo/GO_0004326
• mitochondrial inner membrane
  http://purl.obolibrary.org/obo/GO_0005743
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00790
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Folate biosynthesis
• Metabolic pathways