CD15194

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15194

CD15194

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mlst8

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• MTOR associated protein, LST8 homolog (S. cerevisiae)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• transducin (beta)-like 4
• TORC subunit LST8
• target of rapamycin complex subunit LST8
• MTOR associated protein, LST8 homolog (S. cerevisiae)
• protein GbetaL
• mammalian lethal with SEC13 protein 8

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 0610033N12Rik
• AI851821
• AI505104
• mLST8
• AA409454
• Gbl

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/56716

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• MTOR associated protein, LST8 homolog (S. cerevisiae)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929514

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_019988
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001252465
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001252464
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001252463

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024142

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.289516

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=612190

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Juan M. García-Martínez, et.al., mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)., The Biochemical journal, 2008, 416
  http://rdf.ncbi.nlm.nih.gov/pubmed/18925875
• B D. Rodgers, et.al., Insulin regulation of a novel WD-40 repeat protein in adipocytes., The Journal of endocrinology, 2001, 168
  http://rdf.ncbi.nlm.nih.gov/pubmed/11182770
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821
• Hui H. Zhang, et.al., Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19593385
• Qi. Zhao, et.al., Dominant negative effects of a Gbeta mutant on G-protein coupled inward rectifier K+ channel., FEBS letters, 2006, 580
  http://rdf.ncbi.nlm.nih.gov/pubmed/16797547
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• David A. Guertin, et.al., mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice., Cancer cell, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19185849
• David A. Guertin, et.al., Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1., Developmental cell, 2006, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/17141160
• Partha. Chakrabarti, et.al., Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage., Diabetes, 2010, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/20068142
• Estela. Jacinto, et.al., Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive., Nature cell biology, 2004, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/15467718

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• regulation of actin cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0032956
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• positive regulation of peptidyl-tyrosine phosphorylation
  http://purl.obolibrary.org/obo/GO_0050731
• positive regulation of actin filament polymerization
  http://purl.obolibrary.org/obo/GO_0030838
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• TORC2 complex
  http://purl.obolibrary.org/obo/GO_0031932
• regulation of GTPase activity
  http://purl.obolibrary.org/obo/GO_0043087
• TORC1 complex
  http://purl.obolibrary.org/obo/GO_0031931
• positive regulation of TOR signaling
  http://purl.obolibrary.org/obo/GO_0032008

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04150

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• mTOR signaling pathway