CD15402

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15402

CD15402

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Nr1h2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• nuclear receptor subfamily 1, group H, member 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• LXR beta
• nuclear receptor subfamily 1, group H, member 2
• liver X receptor beta
• ubiquitously-expressed nuclear receptor 2
• retinoid X receptor-interacting protein No.15
• oxysterols receptor LXR-beta

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• RIP15
• NER1
• Unr2
• LXR
• Unr
• LXRB
• LXRbeta
• AI194859
• UR
• OR-1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/22260

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• nuclear receptor subfamily 1, group H, member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352463

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009473

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000060601

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.968

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600380

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Marion. Korach-André, et.al., Both liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21173252
• J J. Repa, et.al., Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers., Science (New York, N.Y.), 2000, 289
  http://rdf.ncbi.nlm.nih.gov/pubmed/10968783
• B. Ganter, et.al., Myb binding sites within the N-ras promoter repress transcription., Oncogene, 1997, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/9244354
• S. Alberti, et.al., Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta., Gene, 2000, 243
  http://rdf.ncbi.nlm.nih.gov/pubmed/10675617
• Rucha. Patel, et.al., LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21123945
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• James J. Donkin, et.al., ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20739291
• J J. Repa, et.al., Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/11090130
• http://rdf.ncbi.nlm.nih.gov/pubmed/20932939
• W. Seol, et.al., Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors., Molecular endocrinology (Baltimore, Md.), 1995, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/7760852

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of cholesterol efflux
  http://purl.obolibrary.org/obo/GO_0010875
• positive regulation of cholesterol transport
  http://purl.obolibrary.org/obo/GO_0032376
• negative regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010629
• positive regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010628
• positive regulation of secretion of lysosomal enzymes
  http://purl.obolibrary.org/obo/GO_0090340
• positive regulation of lipid storage
  http://purl.obolibrary.org/obo/GO_0010884
• ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
  http://purl.obolibrary.org/obo/GO_0004879
• positive regulation of triglyceride biosynthetic process
  http://purl.obolibrary.org/obo/GO_0010867
• retinoic acid receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0048384
• positive regulation of cellular protein metabolic process
  http://purl.obolibrary.org/obo/GO_0032270
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• negative regulation of proteolysis
  http://purl.obolibrary.org/obo/GO_0045861
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• positive regulation of fatty acid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045723
• negative regulation of pinocytosis
  http://purl.obolibrary.org/obo/GO_0048550
• negative regulation of cholesterol storage
  http://purl.obolibrary.org/obo/GO_0010887
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• negative regulation of lipid transport
  http://purl.obolibrary.org/obo/GO_0032369
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• cholesterol homeostasis
  http://purl.obolibrary.org/obo/GO_0042632
• sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity
  http://purl.obolibrary.org/obo/GO_0001133
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• positive regulation of high-density lipoprotein particle assembly
  http://purl.obolibrary.org/obo/GO_0090108
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• cellular lipid metabolic process
  http://purl.obolibrary.org/obo/GO_0044255
• lipid homeostasis
  http://purl.obolibrary.org/obo/GO_0055088
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• steroid hormone mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0043401
• positive regulation of pancreatic juice secretion
  http://purl.obolibrary.org/obo/GO_0090187
• retinoid X receptor binding
  http://purl.obolibrary.org/obo/GO_0046965
• steroid hormone receptor activity
  http://purl.obolibrary.org/obo/GO_0003707
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• positive regulation of lipoprotein lipase activity
  http://purl.obolibrary.org/obo/GO_0051006

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName