CD15419

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15419

CD15419

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pcx

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• pyruvate carboxylase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• pyruvate carboxylase
• pyruvate carboxylase, mitochondrial
• pyruvic carboxylase
• pyruvate decarboxylase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Pc
• Pcb

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18563

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• pyruvate carboxylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:97520

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001162946
• https://www.ncbi.nlm.nih.gov/nuccore/NM_008797

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024892

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.1845

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=608786

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• David J. Pagliarini, et.al., A mitochondrial protein compendium elucidates complex I disease biology., Cell, 2008, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/18614015
• S. Jitrapakdee, et.al., Structural and promoter regions of the murine pyruvate carboxylase gene., Biochemical and biophysical research communications, 2001, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/11554743
• Sarawut. Jitrapakdee, et.al., The peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro., The Journal of biological chemistry, 2005, 280
  http://rdf.ncbi.nlm.nih.gov/pubmed/15917242
• Ansaya. Thonpho, et.al., Identification of the cyclic AMP responsive element (CRE) that mediates transcriptional regulation of the pyruvate carboxylase gene in HepG2 cells., Biochemical and biophysical research communications, 2010, 393
  http://rdf.ncbi.nlm.nih.gov/pubmed/20171190
• S O. Freytag, et.al., Molecular cloning of a cDNA for human pyruvate carboxylase. Structural relationship to other biotin-containing carboxylases and regulation of mRNA content in differentiating preadipocytes., The Journal of biological chemistry, 1984, 259
  http://rdf.ncbi.nlm.nih.gov/pubmed/6548474
• J. Han, et.al., Reduction of islet pyruvate carboxylase activity might be related to the development of type 2 diabetes mellitus in Agouti-K mice., The Journal of endocrinology, 2010, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/19910451
• Sandrine. Da Cruz, et.al., Proteomic analysis of the mouse liver mitochondrial inner membrane., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12865426
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• J. Zhang, et.al., Adipose pyruvate carboxylase: amino acid sequence and domain structure deduced from cDNA sequencing., Proceedings of the National Academy of Sciences of the United States of America, 1993, 90
  http://rdf.ncbi.nlm.nih.gov/pubmed/8446588

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• oxaloacetate metabolic process
  http://purl.obolibrary.org/obo/GO_0006107
• mitochondrial inner membrane
  http://purl.obolibrary.org/obo/GO_0005743
• biotin binding
  http://purl.obolibrary.org/obo/GO_0009374
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• pyruvate carboxylase activity
  http://purl.obolibrary.org/obo/GO_0004736
• carboxylic acid binding
  http://purl.obolibrary.org/obo/GO_0031406
• gluconeogenesis
  http://purl.obolibrary.org/obo/GO_0006094
• pyruvate metabolic process
  http://purl.obolibrary.org/obo/GO_0006090
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00620
• http://www.genome.jp/dbget-bin/www_bget?map00020
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Pyruvate metabolism
• Citrate cycle (TCA cycle)
• Metabolic pathways