CD15689

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15689

CD15689

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Por

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• P450 (cytochrome) oxidoreductase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• P450R
• P450 (cytochrome) oxidoreductase
• NADPH--cytochrome P450 reductase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• CPR
• 4933424M13Rik
• CYPOR
• NADH cytochrome P450 oxydoreductase

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18984

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• P450 (cytochrome) oxidoreductase
  http://metadb.riken.jp/db/mgi_rdf/MGI:97744

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008898

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000005514

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.3863

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=124015

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• S. Ohgiya, et.al., Molecular cloning and sequence analysis of guinea-pig NADPH-cytochrome P-450 oxidoreductase [corrected]., Biochimica et biophysica acta, 1992, 1171
  http://rdf.ncbi.nlm.nih.gov/pubmed/1420354
• D L. Simmons, et.al., Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes., The Journal of biological chemistry, 1985, 260
  http://rdf.ncbi.nlm.nih.gov/pubmed/3917435
• E A. Shephard, et.al., Isolation of a human cytochrome P-450 reductase cDNA clone and localization of the corresponding gene to chromosome 7q11.2., Annals of human genetics, 1989, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/2516426
• Jennie L. Conroy, et.al., Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling., Nature neuroscience, 2010, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/20139973
• F J. Gonzalez, et.al., Cloning of DNA complementary to rat liver NADPH-cytochrome c (P-450) oxidoreductase and cytochrome P-450b mRNAs. Evidence that phenobarbital augments transcription of specific genes., The Journal of biological chemistry, 1982, 257
  http://rdf.ncbi.nlm.nih.gov/pubmed/6802825
• D S. Keeney, et.al., Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1., Molecular endocrinology (Baltimore, Md.), 1995, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/7476982
• Yuan. Wei, et.al., Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression in extrahepatic tissues., The Journal of pharmacology and experimental therapeutics, 2010, 334
  http://rdf.ncbi.nlm.nih.gov/pubmed/20375200
• Fang. Xie, et.al., Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation., Toxicology and applied pharmacology, 2010, 249
  http://rdf.ncbi.nlm.nih.gov/pubmed/20840855
• Anna L. Shen, et.al., The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20808945

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• iron ion binding
  http://purl.obolibrary.org/obo/GO_0005506
• NADP+ binding
  http://purl.obolibrary.org/obo/GO_0070401
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• enzyme binding
  http://purl.obolibrary.org/obo/GO_0019899
• NADP binding
  http://purl.obolibrary.org/obo/GO_0050661
• flavin adenine dinucleotide binding
  http://purl.obolibrary.org/obo/GO_0050660
• negative regulation of lipase activity
  http://purl.obolibrary.org/obo/GO_0060192
• positive regulation of smoothened signaling pathway
  http://purl.obolibrary.org/obo/GO_0045880
• positive regulation of chondrocyte differentiation
  http://purl.obolibrary.org/obo/GO_0032332
• demethylation
  http://purl.obolibrary.org/obo/GO_0070988
• positive regulation of cholesterol biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045542
• cellular organofluorine metabolic process
  http://purl.obolibrary.org/obo/GO_0090346
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• nitric oxide catabolic process
  http://purl.obolibrary.org/obo/GO_0046210
• positive regulation of monooxygenase activity
  http://purl.obolibrary.org/obo/GO_0032770
• iron-cytochrome-c reductase activity
  http://purl.obolibrary.org/obo/GO_0047726
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• positive regulation of steroid hormone biosynthetic process
  http://purl.obolibrary.org/obo/GO_0090031
• regulation of growth plate cartilage chondrocyte proliferation
  http://purl.obolibrary.org/obo/GO_0003420
• cytochrome-b5 reductase activity, acting on NADPH
  http://purl.obolibrary.org/obo/GO_0090523
• internal peptidyl-lysine acetylation
  http://purl.obolibrary.org/obo/GO_0018393
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• FMN binding
  http://purl.obolibrary.org/obo/GO_0010181
• NADPH-hemoprotein reductase activity
  http://purl.obolibrary.org/obo/GO_0003958
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• nitrate catabolic process
  http://purl.obolibrary.org/obo/GO_0043602
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0043154
• regulation of cholesterol metabolic process
  http://purl.obolibrary.org/obo/GO_0090181
• fatty acid oxidation
  http://purl.obolibrary.org/obo/GO_0019395

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName