CD15729

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15729

CD15729

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mapkapk5

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• MAP kinase-activated protein kinase 5

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• MAP kinase-activated protein kinase 5
• MAPKAPK-5
• MAPKAP kinase 5
• MAPK-activated protein kinase 5

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• MK5
• PRAK

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/17165

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• MAP kinase-activated protein kinase 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333110

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010765

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029454

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.272206

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=606723

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Qinxi. Li, et.al., Determinants that control the distinct subcellular localization of p38alpha-PRAK and p38beta-PRAK complexes., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18268017
• Nancy. Gerits, et.al., The transcriptional regulation and cell-specific expression of the MAPK-activated protein kinase MK5., Cellular & molecular biology letters, 2009, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/19484198
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Peiqing. Sun, et.al., PRAK is essential for ras-induced senescence and tumor suppression., Cell, 2007, 128
  http://rdf.ncbi.nlm.nih.gov/pubmed/17254968
• H. Ni, et.al., MAPKAPK5, a novel mitogen-activated protein kinase (MAPK)-activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase., Biochemical and biophysical research communications, 1998, 243
  http://rdf.ncbi.nlm.nih.gov/pubmed/9480836
• Dharmendra. Dingar, et.al., Characterization of the expression and regulation of MK5 in the murine ventricular myocardium., Cellular signalling, 2010, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/20214976
• Ole-Morten. Seternes, et.al., Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway., The EMBO journal, 2004, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/15577943
• Ole Morten. Seternes, et.al., Both binding and activation of p38 mitogen-activated protein kinase (MAPK) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12242275
• Stefanie. Schumacher, et.al., Scaffolding by ERK3 regulates MK5 in development., The EMBO journal, 2004, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/15538386
• Yu. Shi, et.al., Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/14560018

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04010

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• MAPK signaling pathway