CD15792

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15792

CD15792

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Slc6a4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• 5HT transporter
• 5HTT
• 5-hydroxytryptamine (serotonin) transporter
• Sodium-dependent serotonin transporter (5HT transporter) (5HTT)
• solute carrier family 6 member 4
• sodium-dependent serotonin transporter
• solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 5-HTT
• Htt
• Sert
• AI323329

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/15567

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:96285

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010484

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000020838

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.300318

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=182138

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• D S. Choi, et.al., 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells., Development (Cambridge, England), 1997, 124
  http://rdf.ncbi.nlm.nih.gov/pubmed/9165122
• Georgianna G. Gould, et.al., Density and function of central serotonin (5-HT) transporters, 5-HT1A and 5-HT2A receptors, and effects of their targeting on BTBR T+tf/J mouse social behavior., Journal of neurochemistry, 2011, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/21070242
• Nicole. Baganz, et.al., Repeated swim impairs serotonin clearance via a corticosterone-sensitive mechanism: organic cation transporter 3, the smoking gun., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21068324
• D. Bengel, et.al., Gene structure and 5'-flanking regulatory region of the murine serotonin transporter., Brain research. Molecular brain research, 1997, 44
  http://rdf.ncbi.nlm.nih.gov/pubmed/9073170
• P. Gregor, et.al., Murine serotonin transporter: sequence and localization to chromosome 11., Mammalian genome : official journal of the International Mammalian Genome Society, 1993, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/8507984
• S. Ovalle, et.al., Immunodetection of serotonin transporter from mouse brain., Neuroreport, 1995, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/8747152
• Valeria. Carola, et.al., Effect of the interaction between the serotonin transporter gene and maternal environment on developing mouse brain., Behavioural brain research, 2011, 217
  http://rdf.ncbi.nlm.nih.gov/pubmed/20974189
• Hiromasa. Funato, et.al., Loss of Goosecoid-like and DiGeorge syndrome critical region 14 in interpeduncular nucleus results in altered regulation of rapid eye movement sleep., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20921407
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• A S. Chang, et.al., Cloning and expression of the mouse serotonin transporter., Brain research. Molecular brain research, 1996, 43
  http://rdf.ncbi.nlm.nih.gov/pubmed/9037532

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• syntaxin-1 binding
  http://purl.obolibrary.org/obo/GO_0017075
• serotonin transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0015222
• serotonin transport
  http://purl.obolibrary.org/obo/GO_0006837
• negative regulation of synaptic transmission, dopaminergic
  http://purl.obolibrary.org/obo/GO_0032227
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• synaptosome
  http://purl.obolibrary.org/obo/GO_0019717
• cellular response to cGMP
  http://purl.obolibrary.org/obo/GO_0071321
• monoamine transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0008504
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• negative regulation of neuron differentiation
  http://purl.obolibrary.org/obo/GO_0045665
• vasoconstriction
  http://purl.obolibrary.org/obo/GO_0042310
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• thalamus development
  http://purl.obolibrary.org/obo/GO_0021794
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• serotonin:sodium symporter activity
  http://purl.obolibrary.org/obo/GO_0005335
• neurotransmitter:sodium symporter activity
  http://purl.obolibrary.org/obo/GO_0005328
• serotonin uptake
  http://purl.obolibrary.org/obo/GO_0051610
• circadian rhythm
  http://purl.obolibrary.org/obo/GO_0007623
• positive regulation of cell cycle
  http://purl.obolibrary.org/obo/GO_0045787
• negative regulation of cerebellar granule cell precursor proliferation
  http://purl.obolibrary.org/obo/GO_0021941
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• protein homooligomerization
  http://purl.obolibrary.org/obo/GO_0051260
• actin filament binding
  http://purl.obolibrary.org/obo/GO_0051015
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• endosome
  http://purl.obolibrary.org/obo/GO_0005768
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• sperm ejaculation
  http://purl.obolibrary.org/obo/GO_0042713
• sodium ion export from cell
  http://purl.obolibrary.org/obo/GO_0036376
• positive regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010628
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• endomembrane system
  http://purl.obolibrary.org/obo/GO_0012505
• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• monoamine transport
  http://purl.obolibrary.org/obo/GO_0015844
• neurotransmitter transport
  http://purl.obolibrary.org/obo/GO_0006836
• protein oligomerization
  http://purl.obolibrary.org/obo/GO_0051259
• cocaine binding
  http://purl.obolibrary.org/obo/GO_0019811
• Rab GTPase binding
  http://purl.obolibrary.org/obo/GO_0017137
• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• nitric-oxide synthase binding
  http://purl.obolibrary.org/obo/GO_0050998
• memory
  http://purl.obolibrary.org/obo/GO_0007613
• myosin binding
  http://purl.obolibrary.org/obo/GO_0017022
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• symporter activity
  http://purl.obolibrary.org/obo/GO_0015293

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName