CD15877

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15877

CD15877

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cfb

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• complement factor B

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• complement component 2 (within H-2S)
• C3/C5 convertase
• complement factor B
• properdin
• histocompatibility 2, complement component factor B

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• B
• C2
• FB
• AI195813
• alternative-complement pathway C3/C5 convertase
• Bf
• AI255840
• H2-Bf
• Fb
• Factor B

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/14962

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• complement factor B
  http://metadb.riken.jp/db/mgi_rdf/MGI:105975

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008198
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001142706

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000090231

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.653

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=138470

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• J E. Womack, et.al., Mitochondrial malate dehydrogenase (Mor-1) in the mouse: linkage to chromosome 5 markers., Biochemical genetics, 1975, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/1203052
• W P. Lafuse, et.al., Restriction fragment length polymorphism analysis of factor B and C2 genes in H-2 recombinant mouse strains., Immunogenetics, 1990, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/1970336
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• W P. Lafuse, et.al., PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex., Immunogenetics, 1992, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/1351875
• Zhidan. Tu, et.al., Efficient osteoclast differentiation requires local complement activation., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20709903
• N. Ishikawa, et.al., Murine complement C2 and factor B genomic and cDNA cloning reveals different mechanisms for multiple transcripts of C2 and B., The Journal of biological chemistry, 1990, 265
  http://rdf.ncbi.nlm.nih.gov/pubmed/2229060
• Xiaobo. Wu, et.al., Properdin homeostasis requires turnover of the alternative complement pathway., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20974943
• G. Garnier, et.al., cis and trans elements differ among mouse strains with high and low extrahepatic complement factor B gene expression., The Journal of experimental medicine, 1992, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/1370685
• Brandon. Renner, et.al., The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20675597
• Nirmal K. Banda, et.al., Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20870940

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• complement activation
  http://purl.obolibrary.org/obo/GO_0006956
• serine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004252
• innate immune response
  http://purl.obolibrary.org/obo/GO_0045087
• serine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008236
• complement activation, alternative pathway
  http://purl.obolibrary.org/obo/GO_0006957
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• cell proliferation
  http://purl.obolibrary.org/obo/GO_0008283

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04610
• http://www.genome.jp/dbget-bin/www_bget?map05150

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Staphylococcus aureus infection
• Complement and coagulation cascades