CD15883

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15883

CD15883

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cav2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• caveolin 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• caveolin 2
• caveolin-2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI447843

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12390

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• caveolin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:107571

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_016900

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000000058

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.396075

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601048

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Leike. Xie, et.al., Endothelial cells isolated from caveolin-2 knockout mice display higher proliferation rate and cell cycle progression relative to their wild-type counterparts., American journal of physiology. Cell physiology, 2010, 298
  http://rdf.ncbi.nlm.nih.gov/pubmed/20007452
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Kuo-Chen. Wu, et.al., Change in P-glycoprotein and caveolin protein expression in brain striatum capillaries in New Zealand obese mice with type 2 diabetes., Life sciences, 2009, 85
  http://rdf.ncbi.nlm.nih.gov/pubmed/19891976
• T. Okamoto, et.al., Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9488658
• J A. Engelman, et.al., Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy., American journal of human genetics, 1998, 63
  http://rdf.ncbi.nlm.nih.gov/pubmed/9837809
• Xing-Hui. Sun, et.al., A conserved sequence in caveolin-1 is both necessary and sufficient for caveolin polarity and cell directional migration., FEBS letters, 2009, 583
  http://rdf.ncbi.nlm.nih.gov/pubmed/19854179
• Patricia V. Miranda, et.al., Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm., Biology of reproduction, 2009, 80
  http://rdf.ncbi.nlm.nih.gov/pubmed/19144954
• J A. Engelman, et.al., Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9685399
• J A. Engelman, et.al., Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31)., FEBS letters, 1998, 429
  http://rdf.ncbi.nlm.nih.gov/pubmed/9662443
• P E. Scherer, et.al., Identification, sequence, and expression of caveolin-2 defines a caveolin gene family., Proceedings of the National Academy of Sciences of the United States of America, 1996, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/8552590

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• negative regulation of endothelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0001937
• transport vesicle
  http://purl.obolibrary.org/obo/GO_0030133
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• extrinsic component of cytoplasmic side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0031234
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• acrosomal membrane
  http://purl.obolibrary.org/obo/GO_0002080
• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• vesicle organization
  http://purl.obolibrary.org/obo/GO_0016050
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• caveola assembly
  http://purl.obolibrary.org/obo/GO_0070836
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• vesicle docking
  http://purl.obolibrary.org/obo/GO_0048278
• caveola
  http://purl.obolibrary.org/obo/GO_0005901
• D1 dopamine receptor binding
  http://purl.obolibrary.org/obo/GO_0031748
• mitochondrion organization
  http://purl.obolibrary.org/obo/GO_0007005
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• positive regulation of dopamine receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0060161
• endoplasmic reticulum organization
  http://purl.obolibrary.org/obo/GO_0007029
• phosphoprotein binding
  http://purl.obolibrary.org/obo/GO_0051219
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• vesicle fusion
  http://purl.obolibrary.org/obo/GO_0005481
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• protein oligomerization
  http://purl.obolibrary.org/obo/GO_0051259
• synaptic transmission
  http://purl.obolibrary.org/obo/GO_0007268
• syntaxin binding
  http://purl.obolibrary.org/obo/GO_0019905
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• skeletal muscle fiber development
  http://purl.obolibrary.org/obo/GO_0048741
• lipid particle
  http://purl.obolibrary.org/obo/GO_0005811
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• endocytosis
  http://purl.obolibrary.org/obo/GO_0006897
• vesicle fusion
  http://purl.obolibrary.org/obo/GO_0006906
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• SNARE binding
  http://purl.obolibrary.org/obo/GO_0000149

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04510
• http://www.genome.jp/dbget-bin/www_bget?map04144
• http://www.genome.jp/dbget-bin/www_bget?map05100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Endocytosis
• Focal adhesion
• Bacterial invasion of epithelial cells