CD15988

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15988

CD15988

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Trpv4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• transient receptor potential cation channel, subfamily V, member 4

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• transient receptor potential cation channel, subfamily V, member 4
• osm-9-like TRP channel 4
• osmosensitive transient receptor potential channel 4
• vanilloid receptor-like channel 2
• vanilloid receptor-related osmotically-activated channel
• transient receptor potential protein 12
• vanilloid receptor-like protein 2
• transient receptor potential cation channel subfamily V member 4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 0610033B08Rik
• Trp12
• VROAC
• VRL-2
• VR-OAC
• OTRPC4

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/63873

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• transient receptor potential cation channel, subfamily V, member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926945

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_022017

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000014158

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.266450

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605427

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• W. Liedtke, et.al., Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor., Cell, 2000, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/11081638
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Valentina. Benfenati, et.al., An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21262839
• Wouter. Everaerts, et.al., Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20956320
• Thomas. Voets, et.al., Molecular determinants of permeation through the cation channel TRPV4., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/12093812
• Stefan G. Lechner, et.al., The molecular and cellular identity of peripheral osmoreceptors., Neuron, 2011, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/21262470
• Roberta. Zaninetti, et.al., Activation of TRPV4 channels reduces migration of immortalized neuroendocrine cells., Journal of neurochemistry, 2011, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/21166676
• Hiroyuki. Watanabe, et.al., Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11827975
• R. Strotmann, et.al., OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity., Nature cell biology, 2000, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/11025659
• U. Wissenbach, et.al., Trp12, a novel Trp related protein from kidney., FEBS letters, 2000, 485
  http://rdf.ncbi.nlm.nih.gov/pubmed/11094154

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• calcium ion transport
  http://purl.obolibrary.org/obo/GO_0006816
• ruffle membrane
  http://purl.obolibrary.org/obo/GO_0032587
• ion channel activity
  http://purl.obolibrary.org/obo/GO_0005216
• protein kinase C binding
  http://purl.obolibrary.org/obo/GO_0005080
• calcium ion import
  http://purl.obolibrary.org/obo/GO_0070509
• response to osmotic stress
  http://purl.obolibrary.org/obo/GO_0006970
• cytoplasmic microtubule
  http://purl.obolibrary.org/obo/GO_0005881
• calcium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0070588
• regulation of response to osmotic stress
  http://purl.obolibrary.org/obo/GO_0047484
• SH2 domain binding
  http://purl.obolibrary.org/obo/GO_0042169
• cation channel activity
  http://purl.obolibrary.org/obo/GO_0005261
• negative regulation of neuron projection development
  http://purl.obolibrary.org/obo/GO_0010977
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• cortical actin cytoskeleton
  http://purl.obolibrary.org/obo/GO_0030864
• actin binding
  http://purl.obolibrary.org/obo/GO_0003779
• ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034220
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• microtubule binding
  http://purl.obolibrary.org/obo/GO_0008017
• focal adhesion
  http://purl.obolibrary.org/obo/GO_0005925
• cellular hypotonic response
  http://purl.obolibrary.org/obo/GO_0071476
• lamellipodium
  http://purl.obolibrary.org/obo/GO_0030027
• store-operated calcium entry
  http://purl.obolibrary.org/obo/GO_0002115
• positive regulation of cytosolic calcium ion concentration
  http://purl.obolibrary.org/obo/GO_0007204
• osmosensor activity
  http://purl.obolibrary.org/obo/GO_0005034
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• calmodulin binding
  http://purl.obolibrary.org/obo/GO_0005516
• actin filament organization
  http://purl.obolibrary.org/obo/GO_0007015
• osmosensory signaling pathway
  http://purl.obolibrary.org/obo/GO_0007231
• hypotonic response
  http://purl.obolibrary.org/obo/GO_0006971
• actin filament binding
  http://purl.obolibrary.org/obo/GO_0051015
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• hyperosmotic salinity response
  http://purl.obolibrary.org/obo/GO_0042538
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• cortical microtubule organization
  http://purl.obolibrary.org/obo/GO_0043622
• vasopressin secretion
  http://purl.obolibrary.org/obo/GO_0030103
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• cell-cell junction assembly
  http://purl.obolibrary.org/obo/GO_0007043
• microtubule polymerization
  http://purl.obolibrary.org/obo/GO_0046785
• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• growth cone
  http://purl.obolibrary.org/obo/GO_0030426
• beta-tubulin binding
  http://purl.obolibrary.org/obo/GO_0048487
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• adherens junction
  http://purl.obolibrary.org/obo/GO_0005912
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• filopodium
  http://purl.obolibrary.org/obo/GO_0030175
• cilium
  http://purl.obolibrary.org/obo/GO_0005929
• cellular calcium ion homeostasis
  http://purl.obolibrary.org/obo/GO_0006874
• alpha-tubulin binding
  http://purl.obolibrary.org/obo/GO_0043014
• calcium channel activity
  http://purl.obolibrary.org/obo/GO_0005262
• actin cytoskeleton reorganization
  http://purl.obolibrary.org/obo/GO_0031532
• positive regulation of microtubule depolymerization
  http://purl.obolibrary.org/obo/GO_0031117

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName