CD15989

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15989

CD15989

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Il2rb

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• interleukin 2 receptor, beta chain

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• IL-2RB
• interleukin-2 receptor subunit beta
• interleukin 2 receptor, beta chain
• IL-2R subunit beta
• p70-75
• high affinity IL-2 receptor subunit beta
• IL-2/15 receptor-beta
• IL-2 receptor beta chain
• IL-2 receptor subunit beta

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• IL15Rbeta
• Il-2Rbeta
• IL-15Rbeta
• IL-2/15Rbeta
• p70
• Il-2/15Rbeta
• IL-15 receptor beta chain
• CD122

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16185

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• interleukin 2 receptor, beta chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:96550

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008368

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000068227

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.35287

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=146710

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• T. Kono, et.al., Murine interleukin 2 receptor beta chain: dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion., Proceedings of the National Academy of Sciences of the United States of America, 1990, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/2155425
• L S. Casey, et.al., IL-4 induces IL-2 receptor p75 beta-chain gene expression and IL-2-dependent proliferation in mouse T lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 1992, 148
  http://rdf.ncbi.nlm.nih.gov/pubmed/1588041
• H D. Campbell, et.al., Assignment of the interleukin-2 receptor beta chain gene (Il-2rb) to band E on mouse chromosome 15., Genomics, 1992, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/1733860
• Kazuyo. Moro, et.al., Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells., Nature, 2010, 463
  http://rdf.ncbi.nlm.nih.gov/pubmed/20023630
• Naoko. Satoh-Takayama, et.al., The natural cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium., Journal of immunology (Baltimore, Md. : 1950), 2009, 183
  http://rdf.ncbi.nlm.nih.gov/pubmed/19846871
• Taylor H. Schreiber, et.al., Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890040
• I. Berberich, et.al., Regulation of immunoglobulin gene expression in normal lymphocytes. II. Mechanisms of down-regulation of immunoglobulin secretion after engagement of the B cell antigen receptor., European journal of immunology, 1992, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/1537386
• Laurye. Van Maele, et.al., TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20566828
• R A. Montgomery, et.al., Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction., Journal of immunology (Baltimore, Md. : 1950), 1991, 147
  http://rdf.ncbi.nlm.nih.gov/pubmed/1649220

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytokine receptor activity
  http://purl.obolibrary.org/obo/GO_0004896
• cytokine-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0019221
• interleukin-2 receptor activity
  http://purl.obolibrary.org/obo/GO_0004911
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• natural killer cell activation
  http://purl.obolibrary.org/obo/GO_0030101
• positive regulation of survival gene product expression
  http://purl.obolibrary.org/obo/GO_0045885
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• interleukin-2 binding
  http://purl.obolibrary.org/obo/GO_0019976
• membrane
  http://purl.obolibrary.org/obo/GO_0016020

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04144
• http://www.genome.jp/dbget-bin/www_bget?map04060
• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map05202
• http://www.genome.jp/dbget-bin/www_bget?map05162
• http://www.genome.jp/dbget-bin/www_bget?map04630

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Jak-STAT signaling pathway
• Endocytosis
• Measles
• Cytokine-cytokine receptor interaction
• HTLV-I infection
• Transcriptional misregulation in cancers