CD16027

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16027

CD16027

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Apoa5

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• apolipoprotein A-V

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• apoA-V
• regeneration-associated protein 3
• apolipoprotein A-V
• apo-AV
• apolipoprotein A5

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Apoav
• 1300007O05Rik
• RAP3

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/66113

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• apolipoprotein A-V
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913363

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_080434

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000032079

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.29738

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=606368

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Kasuen. Wong-Mauldin, et.al., Apolipoprotein A-V N-terminal domain lipid interaction properties in vitro explain the hypertriglyceridemic phenotype associated with natural truncation mutants., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19825998
• Hendrik N. van der Vliet, et.al., Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice., Biochemical and biophysical research communications, 2002, 295
  http://rdf.ncbi.nlm.nih.gov/pubmed/12135615
• Alexander. Bartelt, et.al., Brown adipose tissue activity controls triglyceride clearance., Nature medicine, 2011, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/21258337
• Ephraim. Sehayek, et.al., Loci controlling plasma non-HDL and HDL cholesterol levels in a C57BL /6J x CASA /Rk intercross., Journal of lipid research, 2003, 44
  http://rdf.ncbi.nlm.nih.gov/pubmed/12810823
• Xiao. Shu, et.al., Apolipoprotein A-V associates with intrahepatic lipid droplets and influences triglyceride accumulation., Biochimica et biophysica acta, 2010, 1801
  http://rdf.ncbi.nlm.nih.gov/pubmed/20153840
• Xiao. Shu, et.al., Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1., Arteriosclerosis, thrombosis, and vascular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20966404
• L A. Pennacchio, et.al., An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing., Science (New York, N.Y.), 2001, 294
  http://rdf.ncbi.nlm.nih.gov/pubmed/11588264
• H N. van der Vliet, et.al., Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11577099
• Len A. Pennacchio, et.al., Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice., Arteriosclerosis, thrombosis, and vascular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12615678

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of lipoprotein lipase activity
  http://purl.obolibrary.org/obo/GO_0051006
• high-density lipoprotein particle
  http://purl.obolibrary.org/obo/GO_0034364
• lipoprotein lipase activator activity
  http://purl.obolibrary.org/obo/GO_0060230
• lipid transport
  http://purl.obolibrary.org/obo/GO_0006869
• lipoprotein particle receptor binding
  http://purl.obolibrary.org/obo/GO_0070325
• lipoprotein metabolic process
  http://purl.obolibrary.org/obo/GO_0042157
• triglyceride homeostasis
  http://purl.obolibrary.org/obo/GO_0070328
• heparin binding
  http://purl.obolibrary.org/obo/GO_0008201
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• positive regulation of triglyceride catabolic process
  http://purl.obolibrary.org/obo/GO_0010898
• lipid binding
  http://purl.obolibrary.org/obo/GO_0008289
• enzyme binding
  http://purl.obolibrary.org/obo/GO_0019899
• chylomicron
  http://purl.obolibrary.org/obo/GO_0042627
• positive regulation of lipid catabolic process
  http://purl.obolibrary.org/obo/GO_0050996
• low-density lipoprotein particle receptor binding
  http://purl.obolibrary.org/obo/GO_0050750
• lipid binding
  http://purl.obolibrary.org/obo/GO_0006630
• enzyme activator activity
  http://purl.obolibrary.org/obo/GO_0008047
• cholesterol homeostasis
  http://purl.obolibrary.org/obo/GO_0042632
• lipase activator activity
  http://purl.obolibrary.org/obo/GO_0060229
• triglyceride catabolic process
  http://purl.obolibrary.org/obo/GO_0019433
• phospholipid binding
  http://purl.obolibrary.org/obo/GO_0005543
• triglyceride metabolic process
  http://purl.obolibrary.org/obo/GO_0006641
• acylglycerol homeostasis
  http://purl.obolibrary.org/obo/GO_0055090
• positive regulation of fatty acid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045723
• phosphatidylcholine binding
  http://purl.obolibrary.org/obo/GO_0031210
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• triglyceride-rich lipoprotein particle remodeling
  http://purl.obolibrary.org/obo/GO_0034370
• very-low-density lipoprotein particle
  http://purl.obolibrary.org/obo/GO_0034361
• positive regulation of very-low-density lipoprotein particle remodeling
  http://purl.obolibrary.org/obo/GO_0010902

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map03320

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• PPAR signaling pathway