CD16108

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16108

CD16108

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Itga2b

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• integrin alpha 2b

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• GPalpha IIb
• alpha IIb
• platelet glycoprotein IIb of IIb/II Ia complex
• platelet membrane glycoprotein IIb
• integrin alpha 2b
• integrin alpha-IIb

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• GP IIb
• GpIIb
• CD41B
• AI172977
• alphaIIb
• CD41
• platelet glycoprotein IIb

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16399

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• integrin alpha 2b
  http://metadb.riken.jp/db/mgi_rdf/MGI:96601

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010575

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000034664

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.26646

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=607759

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Moritz. Stolla, et.al., The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy., Blood, 2011, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/20971951
• R A. Shivdasani, et.al., Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development., Cell, 1995, 81
  http://rdf.ncbi.nlm.nih.gov/pubmed/7774011
• Yasuka L. Yamaguchi, et.al., Translocon-associated protein subunit Trap-γ/Ssr3 is required for vascular network formation in the mouse placenta., Developmental dynamics : an official publication of the American Association of Anatomists, 2011, 240
  http://rdf.ncbi.nlm.nih.gov/pubmed/21246656
• Y Q. Chen, et.al., Identification of the alpha IIb beta 3 integrin in murine tumor cells., The Journal of biological chemistry, 1992, 267
  http://rdf.ncbi.nlm.nih.gov/pubmed/1512266
• H C. Morse, Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells., Journal of immunology (Baltimore, Md. : 1950), 1992, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/1431091
• E. Denarier, et.al., PCR cloning and sequence of the murine GPIIb gene promoter., Biochemical and biophysical research communications, 1993, 195
  http://rdf.ncbi.nlm.nih.gov/pubmed/8216269
• Tatsuya. Sasaki, et.al., Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/20980401
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• D R. Phillips, et.al., GPIIb-IIIa: the responsive integrin., Cell, 1991, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/2018971
• Antreas C. Kalli, et.al., The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study., Structure (London, England : 1993), 2010, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/20947017

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cell-matrix adhesion
  http://purl.obolibrary.org/obo/GO_0007160
• cell adhesion
  http://purl.obolibrary.org/obo/GO_0007155
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• positive regulation of leukocyte migration
  http://purl.obolibrary.org/obo/GO_0002687
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• platelet aggregation
  http://purl.obolibrary.org/obo/GO_0070527
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• integrin-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0007229
• focal adhesion
  http://purl.obolibrary.org/obo/GO_0005925
• integrin complex
  http://purl.obolibrary.org/obo/GO_0008305
• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• extracellular matrix binding
  http://purl.obolibrary.org/obo/GO_0050840
• fibrinogen binding
  http://purl.obolibrary.org/obo/GO_0070051

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05222
• http://www.genome.jp/dbget-bin/www_bget?map04810
• http://www.genome.jp/dbget-bin/www_bget?map04512
• http://www.genome.jp/dbget-bin/www_bget?map05414
• http://www.genome.jp/dbget-bin/www_bget?map05410
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map04510
• http://www.genome.jp/dbget-bin/www_bget?map05412
• http://www.genome.jp/dbget-bin/www_bget?map04640

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Pathways in cancer
• Dilated cardiomyopathy
• Arrhythmogenic right ventricular cardiomyopathy (ARVC)
• Hematopoietic cell lineage
• Regulation of actin cytoskeleton
• Focal adhesion
• ECM-receptor interaction
• Small cell lung cancer
• Hypertrophic cardiomyopathy (HCM)