CD16127

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16127

CD16127

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ccl11

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• chemokine (C-C motif) ligand 11

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• small-inducible cytokine A11
• C-C motif chemokine 11
• chemokine (C-C motif) ligand 11
• small chemokine (C-C motif) ligand 11
• small inducible cytokine A11
• eosinophil chemotactic protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Scya11
• eotaxin

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20292

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• chemokine (C-C motif) ligand 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:103576

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011330

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000020676

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.4686

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601156

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• J A. Ganzalo, et.al., Mouse Eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response., Immunity, 1996, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/8574847
• D A. Swartz, et.al., The e subunit gene of murine F1F0-ATP synthase. Genomic sequence, chromosomal mapping, and diet regulation., The Journal of biological chemistry, 1996, 271
  http://rdf.ncbi.nlm.nih.gov/pubmed/8702853
• Eric J. Albert, et.al., Tissue eosinophilia in a mouse model of colitis is highly dependent on TLR2 and independent of mast cells., The American journal of pathology, 2011, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/21224053
• Arthur. Wang, et.al., Exacerbation of oxazolone colitis by infection with the helminth Hymenolepis diminuta: involvement of IL-5 and eosinophils., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/21037078
• M E. Rothenberg, et.al., Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7568052
• P J. Jose, et.al., Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation., The Journal of experimental medicine, 1994, 179
  http://rdf.ncbi.nlm.nih.gov/pubmed/7509365
• Tulio. Queto, et.al., Cysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow., Journal of leukocyte biology, 2010, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/20219953
• Deepti R. Nagarkar, et.al., Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20644177
• M E. Rothenberg, et.al., Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung., The Journal of experimental medicine, 1995, 181
  http://rdf.ncbi.nlm.nih.gov/pubmed/7869037
• C V. Neilsen, et.al., Interleukin-13 directly promotes oesophagus production of CCL11 and CCL24 and the migration of eosinophils., Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2010, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/20030665

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030335
• positive regulation of angiogenesis
  http://purl.obolibrary.org/obo/GO_0045766
• positive regulation of endothelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0001938
• mammary duct terminal end bud growth
  http://purl.obolibrary.org/obo/GO_0060763
• positive regulation of actin filament polymerization
  http://purl.obolibrary.org/obo/GO_0030838
• chemotaxis
  http://purl.obolibrary.org/obo/GO_0006935
• chemokine activity
  http://purl.obolibrary.org/obo/GO_0008009
• inflammatory response
  http://purl.obolibrary.org/obo/GO_0006954
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• eosinophil chemotaxis
  http://purl.obolibrary.org/obo/GO_0048245
• actin filament organization
  http://purl.obolibrary.org/obo/GO_0007015
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• positive regulation of GTPase activity
  http://purl.obolibrary.org/obo/GO_0043547
• ERK1 and ERK2 cascade
  http://purl.obolibrary.org/obo/GO_0070371
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• cytokine activity
  http://purl.obolibrary.org/obo/GO_0005125
• immune response
  http://purl.obolibrary.org/obo/GO_0006955
• mast cell chemotaxis
  http://purl.obolibrary.org/obo/GO_0002551
• branching involved in mammary gland duct morphogenesis
  http://purl.obolibrary.org/obo/GO_0060444

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04062
• http://www.genome.jp/dbget-bin/www_bget?map05310
• http://www.genome.jp/dbget-bin/www_bget?map04060

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Chemokine signaling pathway
• Asthma
• Cytokine-cytokine receptor interaction