CD16427

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16427

CD16427

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Lhx2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• LIM homeobox protein 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• LIM homeo box protein 2
• homeobox protein LH-2
• LIM/homeobox protein Lhx2
• LIM homeobox protein 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• LH2A
• apterous
• ap
• Lh-2
• Lim2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16870

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• LIM homeobox protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96785

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010710

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000000247

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.142856

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603759

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Alisa S W. Shum, et.al., Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube., Developmental dynamics : an official publication of the American Association of Anatomists, 2010, 239
  http://rdf.ncbi.nlm.nih.gov/pubmed/20960561
• Y. Xu, et.al., LH-2: a LIM/homeodomain gene expressed in developing lymphocytes and neural cells., Proceedings of the National Academy of Sciences of the United States of America, 1993, 90
  http://rdf.ncbi.nlm.nih.gov/pubmed/7678338
• Alfonso. Lavado, et.al., Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis., PLoS biology, 2010, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/20808958
• K. Matsumoto, et.al., Differential expression of LIM-homeodomain genes in the embryonic murine brain., Neuroscience letters, 1996, 211
  http://rdf.ncbi.nlm.nih.gov/pubmed/8817562
• A. Wanaka, et.al., LIM-homeodomain gene family in neural development., Developmental neuroscience, 1997, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/9078439
• N. Ben-Arie, et.al., Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis., Human molecular genetics, 1996, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/8872459
• Wei. Liu, et.al., Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890044
• Dario. Magnani, et.al., The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20943929
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• S L. Pfaff, et.al., Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation., Cell, 1996, 84
  http://rdf.ncbi.nlm.nih.gov/pubmed/8565076

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• brain development
  http://purl.obolibrary.org/obo/GO_0007420
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• anatomical structure formation involved in morphogenesis
  http://purl.obolibrary.org/obo/GO_0048646
• axon guidance
  http://purl.obolibrary.org/obo/GO_0007411
• dorsal/ventral pattern formation
  http://purl.obolibrary.org/obo/GO_0009953
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• regulation of RNA biosynthetic process
  http://purl.obolibrary.org/obo/GO_2001141
• neural tube closure
  http://purl.obolibrary.org/obo/GO_0001843
• negative regulation of transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_2000678
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• neurogenesis
  http://purl.obolibrary.org/obo/GO_0022008
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• mesoderm development
  http://purl.obolibrary.org/obo/GO_0007498
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• protein binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0000988
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• nervous system development
  http://purl.obolibrary.org/obo/GO_0007399
• neuron differentiation
  http://purl.obolibrary.org/obo/GO_0030182
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• telencephalon development
  http://purl.obolibrary.org/obo/GO_0021537
• telencephalon regionalization
  http://purl.obolibrary.org/obo/GO_0021978
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName