CD16618

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16618

CD16618

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Lcp2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• lymphocyte cytosolic protein 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• SH2 domain-containing leukocyte protein of 76 kDa
• SLP-76 tyrosine phosphoprotein
• lymphocyte cytosolic protein 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• SLP76
• SLP-76
• twm
• BB161688
• AI323664

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16822

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• lymphocyte cytosolic protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1321402

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010696

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000002699

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.265350

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601603

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• J L. Clements, et.al., Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice., The Journal of clinical investigation, 1999, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/9884330
• J L. Clements, et.al., Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development., Science (New York, N.Y.), 1998, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/9665885
• Taku. Kambayashi, et.al., Independent and cooperative roles of adaptor molecules in proximal signaling during FcepsilonRI-mediated mast cell activation., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20606011
• Irene M. Patzak, et.al., HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion., European journal of immunology, 2010, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/20957749
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Jennifer E. Smith-Garvin, et.al., T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20847203
• J K. Jackman, et.al., Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7706237
• V. Pivniouk, et.al., Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76., Cell, 1998, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9695951
• Karla R. Wiehagen, et.al., Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20884806
• V I. Pivniouk, et.al., SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells., The Journal of clinical investigation, 1999, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/10377180

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cell
  http://purl.obolibrary.org/obo/GO_0005623
• cytokine secretion
  http://purl.obolibrary.org/obo/GO_0050663
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• mast cell activation
  http://purl.obolibrary.org/obo/GO_0045576

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04664
• http://www.genome.jp/dbget-bin/www_bget?map04380
• http://www.genome.jp/dbget-bin/www_bget?map04660
• http://www.genome.jp/dbget-bin/www_bget?map04650

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Fc epsilon RI signaling pathway
• T cell receptor signaling pathway
• Natural killer cell mediated cytotoxicity
• Osteoclast differentiation