CD16644

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16644

CD16644

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Serpind1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• serine (or cysteine) peptidase inhibitor, clade D, member 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• heparin cofactor 2
• HC-II
• serine (or cysteine) peptidase inhibitor, clade D, member 1
• serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1
• serpin D1
• protease inhibitor leuserpin-2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Hcf2
• HC II
• AI303446
• HCII
• heparin cofactor II
• AA985900

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/15160

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• serine (or cysteine) peptidase inhibitor, clade D, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96051

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008223

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022766

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.6609

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=142360

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• I. Ben-Porath, et.al., Chromosomal mapping of Tmp (Emp1), Xmp (Emp2), and Ymp (Emp3), genes encoding membrane proteins related to Pmp22., Genomics, 1998, 49
  http://rdf.ncbi.nlm.nih.gov/pubmed/9615230
• A. Puech, et.al., Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9405660
• G S. Zhang, et.al., Murine heparin cofactor II: purification, cDNA sequence, expression, and gene structure., Biochemistry, 1994, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/7908224
• Jason S. Sutherland, et.al., The appended tail region of heparin cofactor II and additional reactive centre loop mutations combine to increase the reactivity and specificity of alpha1-proteinase inhibitor M358R for thrombin., Thrombosis and haemostasis, 2007, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/18000606
• Cristina P. Vicente, et.al., Accelerated atherogenesis and neointima formation in heparin cofactor II deficient mice., Blood, 2007, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/17878401
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Li. He, et.al., Vascular dermatan sulfate regulates the antithrombotic activity of heparin cofactor II., Blood, 2008, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/18281504
• Ken-ichi. Aihara, et.al., Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II-deficient mice., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17549254
• D. Sinha, et.al., Cloning and mapping the mouse Crygs gene and non-lens expression of [gamma]S-crystallin., Molecular vision, 1998, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/9565648
• H F. Sutherland, et.al., Cloning and comparative mapping of the DiGeorge syndrome critical region in the mouse., Genomics, 1998, 52
  http://rdf.ncbi.nlm.nih.gov/pubmed/9740669

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• blood coagulation
  http://purl.obolibrary.org/obo/GO_0007596
• peptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0030414
• serine-type endopeptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0004867
• heparin binding
  http://purl.obolibrary.org/obo/GO_0008201
• negative regulation of peptidase activity
  http://purl.obolibrary.org/obo/GO_0010466
• negative regulation of endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0010951
• regulation of proteolysis
  http://purl.obolibrary.org/obo/GO_0030162

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04610

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Complement and coagulation cascades