CD16646

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16646

CD16646

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Lin7b

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• lin-7 homolog B (C. elegans)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• mammalian lin-seven protein 2
• veli-2
• protein lin-7 homolog B
• lin-7 homolog B (C. elegans)
• lin 7 homolog b
• vertebrate homolog of C. elegans Lin-7 type 2
• vertebrate lin-7 homolog 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• LIN-7B
• MALS-2
• Veli2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/22342

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• lin-7 homolog B (C. elegans)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1330858

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011698

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000003872

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.20472

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=612331

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M. Setou, et.al., Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport., Science (New York, N.Y.), 2000, 288
  http://rdf.ncbi.nlm.nih.gov/pubmed/10846156
• Karpagam. Srinivasan, et.al., MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex., Development (Cambridge, England), 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/18403412
• S. Butz, et.al., A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain., Cell, 1998, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9753324
• Olav. Olsen, et.al., Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice., The Journal of cell biology, 2007, 179
  http://rdf.ncbi.nlm.nih.gov/pubmed/17923534
• Birgit. Zucker, et.al., Decreased Lin7b expression in layer 5 pyramidal neurons may contribute to impaired corticostriatal connectivity in huntington disease., Journal of neuropathology and experimental neurology, 2010, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/20720508
• Wei. Feng, et.al., A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/15863617
• Larissa. Lozovatsky, et.al., CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity., Molecular biology of the cell, 2009, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/19726564
• Olav. Olsen, et.al., Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex., The Journal of cell biology, 2005, 170
  http://rdf.ncbi.nlm.nih.gov/pubmed/16186258
• K. Jo, et.al., Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex., The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/10341223
• H. Misawa, et.al., Contrasting localizations of MALS/LIN-7 PDZ proteins in brain and molecular compensation in knockout mice., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11104771

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• exocytosis
  http://purl.obolibrary.org/obo/GO_0006887
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• protein transport
  http://purl.obolibrary.org/obo/GO_0015031
• synapse
  http://purl.obolibrary.org/obo/GO_0045202
• postsynaptic membrane
  http://purl.obolibrary.org/obo/GO_0045211
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• protein domain specific binding
  http://purl.obolibrary.org/obo/GO_0019904
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• synaptosome
  http://purl.obolibrary.org/obo/GO_0019717
• cell-cell junction
  http://purl.obolibrary.org/obo/GO_0005911
• neurotransmitter secretion
  http://purl.obolibrary.org/obo/GO_0007269

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName