CD16745

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16745

CD16745

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cyp2a12

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• cytochrome P450, family 2, subfamily a, polypeptide 12

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• cytochrome P450 2A12
• testosterone 7-alpha-hydroxylase
• steroid hormones 7-alpha-hydroxylase
• cytochrome P450, 2a12
• cytochrome P450, family 2, subfamily a, polypeptide 12
• CYPIIA12

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13085

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• cytochrome P450, family 2, subfamily a, polypeptide 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:105055

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_133657

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000060407

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.20770

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• D. Choudhary, et.al., Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues., Archives of biochemistry and biophysics, 2003, 414
  http://rdf.ncbi.nlm.nih.gov/pubmed/12745259
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Haoyi. Wang, et.al., Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster., Environmental health perspectives, 2003, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/14630516
• M. Iwasaki, et.al., Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction., The Biochemical journal, 1993, 291 ( Pt 2)
  http://rdf.ncbi.nlm.nih.gov/pubmed/8484736
• Jaeick. Lee, et.al., Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS., Molecular & cellular proteomics : MCP, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17208939

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  http://purl.obolibrary.org/obo/GO_0016705
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
  http://purl.obolibrary.org/obo/GO_0016712
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• monooxygenase activity
  http://purl.obolibrary.org/obo/GO_0004497
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• steroid hydroxylase activity
  http://purl.obolibrary.org/obo/GO_0008395
• heme binding
  http://purl.obolibrary.org/obo/GO_0020037
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• iron ion binding
  http://purl.obolibrary.org/obo/GO_0005506
• coumarin metabolic process
  http://purl.obolibrary.org/obo/GO_0009804
• aromatase activity
  http://purl.obolibrary.org/obo/GO_0070330

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00980
• http://www.genome.jp/dbget-bin/www_bget?map00982
• http://www.genome.jp/dbget-bin/www_bget?map00232
• http://www.genome.jp/dbget-bin/www_bget?map00830
• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map00983

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Metabolic pathways
• Drug metabolism - cytochrome P450
• Drug metabolism - other enzymes
• Caffeine metabolism
• Metabolism of xenobiotics by cytochrome P450
• Retinol metabolism