CD16750

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16750

CD16750

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cd79a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• CD79A antigen (immunoglobulin-associated alpha)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• membrane-bound immunoglobulin-associated protein
• CD79A antigen (immunoglobulin-associated alpha)
• surface IgM-associated protein
• immunoglobulin-associated alpha
• MB-1 membrane glycoprotein
• B-cell antigen receptor complex-associated protein alpha chain

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• mb-1
• Ly-54
• Iga
• Cd79a
• Ly54
• Igalpha
• Ig-alpha
• Ig alpha

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12518

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007655

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000003379

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.1355

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=112205

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K S. Campbell, et.al., IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes., Proceedings of the National Academy of Sciences of the United States of America, 1991, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/2023945
• A. Travis, et.al., Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences., Molecular and cellular biology, 1991, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/1922076
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Beate. Heizmann, et.al., Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20940318
• L. Matsuuchi, et.al., The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line., Proceedings of the National Academy of Sciences of the United States of America, 1992, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/1373499
• Sarah L. Rowland, et.al., BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20861359
• Pankaj Kumar. Mandal, et.al., Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/21045148
• H. Flaswinkel, et.al., Molecular cloning of the Ig-alpha subunit of the human B-cell antigen receptor complex., Immunogenetics, 1992, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/1639443
• Rebecca. Winkelmann, et.al., B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21187409
• J. Hombach, et.al., Identification of the genes encoding the IgM-alpha and Ig-beta components of the IgM antigen receptor complex by amino-terminal sequencing., European journal of immunology, 1990, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/2269334

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• B cell receptor complex
  http://purl.obolibrary.org/obo/GO_0019815
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• B cell activation
  http://purl.obolibrary.org/obo/GO_0042113
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• B cell receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0050853
• multivesicular body
  http://purl.obolibrary.org/obo/GO_0005771
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• B cell proliferation
  http://purl.obolibrary.org/obo/GO_0042100
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cell surface receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007166
• transmembrane signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0004888
• B cell differentiation
  http://purl.obolibrary.org/obo/GO_0030183

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05340
• http://www.genome.jp/dbget-bin/www_bget?map04662

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• B cell receptor signaling pathway
• Primary immunodeficiency