CD16858

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16858

CD16858

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Bcl2a1a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• B-cell leukemia/lymphoma 2 related protein A1a

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• B-cell leukemia/lymphoma 2 related protein A1a
• bcl-2-related protein A1
• protein BFL-1
• hemopoietic-specific early response protein
• A1-A

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Bfl-1
• A1
• BB218357
• Hbpa1
• Bcl2a1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12044

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• B cell leukemia/lymphoma 2 related protein A1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:102687

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009742

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000074147

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.425593
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.479217

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601056

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Erik. Ullerås, et.al., NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells., Blood, 2008, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/18182578
• D L. Evans, et.al., Molecular evolution and secondary structural conservation in the B-cell lymphoma leukemia 2 (bcl-2) family of proto-oncogene products., Journal of molecular evolution, 1995, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/8587122
• C. Crosio, et.al., Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis., Cell death and differentiation, 2006, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/16710367
• Roberto. Carrio, et.al., Impaired thymopoiesis occurring during the thymic involution of tumor-bearing mice is associated with a down-regulation of the antiapoptotic proteins Bcl-XL and A1., International journal of molecular medicine, 2009, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/19082511
• Reuven. Rasooly, et.al., Retinoid x receptor agonists increase bcl2a1 expression and decrease apoptosis of naive T lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 2005, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/16339527
• E Y. Lin, et.al., Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2., Journal of immunology (Baltimore, Md. : 1950), 1993, 151
  http://rdf.ncbi.nlm.nih.gov/pubmed/8345191
• Gaofeng. Fan, et.al., Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/20185581
• M S. Choi, et.al., Expression of bcl-x during mouse B cell differentiation and following activation by various stimuli., European journal of immunology, 1996, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/8605937
• A. Karsan, et.al., Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells., Blood, 1996, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/8605321
• S S. Choi, et.al., A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow., Oncogene, 1995, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/7478596

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• B cell homeostasis
  http://purl.obolibrary.org/obo/GO_0001782
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0042981
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05202

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Transcriptional misregulation in cancers