CD16922

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16922

CD16922

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ophn1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• oligophrenin 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• oligophrenin-1
• oligophrenin 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• C130037N19Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/94190

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• oligophrenin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2151070

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_052976

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000031214

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.254336

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=300127

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Fabien. Fauchereau, et.al., The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain., Molecular and cellular neurosciences, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12932438
• Akiko. Nakano-Kobayashi, et.al., The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1., Current biology : CB, 2009, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/19481455
• Malik. Khelfaoui, et.al., Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation., Human molecular genetics, 2009, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/19401298
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821
• Malik. Khelfaoui, et.al., Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17728457
• Cyrille. Vaillend, et.al., Genes, plasticity and mental retardation., Behavioural brain research, 2008, 192
  http://rdf.ncbi.nlm.nih.gov/pubmed/18329113

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• ionotropic glutamate receptor binding
  http://purl.obolibrary.org/obo/GO_0035255
• nervous system development
  http://purl.obolibrary.org/obo/GO_0007399
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• cell projection
  http://purl.obolibrary.org/obo/GO_0042995
• actin cytoskeleton
  http://purl.obolibrary.org/obo/GO_0015629
• positive regulation of GTPase activity
  http://purl.obolibrary.org/obo/GO_0043547
• filopodium assembly
  http://purl.obolibrary.org/obo/GO_0046847
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• SH3 domain binding
  http://purl.obolibrary.org/obo/GO_0017124
• actin cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0030036
• synaptic vesicle endocytosis
  http://purl.obolibrary.org/obo/GO_0048488
• actin binding
  http://purl.obolibrary.org/obo/GO_0003779
• terminal bouton
  http://purl.obolibrary.org/obo/GO_0043195
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• GTPase activator activity
  http://purl.obolibrary.org/obo/GO_0005096
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• cytoskeletal adaptor activity
  http://purl.obolibrary.org/obo/GO_0008093
• regulation of endocytosis
  http://purl.obolibrary.org/obo/GO_0030100
• regulation of synaptic transmission, glutamatergic
  http://purl.obolibrary.org/obo/GO_0051966
• synapse
  http://purl.obolibrary.org/obo/GO_0045202
• endocytosis
  http://purl.obolibrary.org/obo/GO_0006897

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName