CD17007

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17007

CD17007

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Tbxa2r

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• thromboxane A2 receptor

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• thromboxane A2 receptor
• prostanoid TP receptor
• TXA2-R

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• TXA2
• Tp receptor
• TP

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/21390

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• thromboxane A2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:98496

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009325

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000034881

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.4545

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=188070

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Toru. Oga, et.al., Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta., Nature medicine, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19966781
• F. Ushikubi, et.al., Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis., The Journal of experimental medicine, 1993, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/8228829
• Miao. Zhang, et.al., Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase., Arteriosclerosis, thrombosis, and vascular biology, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/20947827
• A M. Duncan, et.al., Chromosomal localization of the human prostanoid receptor gene family., Genomics, 1995, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/7759114
• Yoshiyasu. Esaki, et.al., Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20566843
• K. Asano, et.al., Distribution of thromboxane A2 receptor mRNA along the mouse nephron segments., Biochemical and biophysical research communications, 1996, 226
  http://rdf.ncbi.nlm.nih.gov/pubmed/8831666
• S. Watson, et.al., Phenotypic approaches to gene mapping in platelet function disorders - identification of new variant of P2Y12, TxA2 and GPVI receptors., Hamostaseologie, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20162250
• Tillmann. Cyrus, et.al., Expression of thromboxane synthase, prostacyclin synthase and thromboxane receptor in atherosclerotic lesions: correlation with plaque composition., Atherosclerosis, 2010, 208
  http://rdf.ncbi.nlm.nih.gov/pubmed/19735918
• T. Namba, et.al., Mouse thromboxane A2 receptor: cDNA cloning, expression and northern blot analysis., Biochemical and biophysical research communications, 1992, 184
  http://rdf.ncbi.nlm.nih.gov/pubmed/1375456
• M. Taketo, et.al., Mapping of the genes encoding mouse thromboxane A2 receptor and prostaglandin E receptor subtypes EP2 and EP3., Genomics, 1994, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/7910583

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• positive regulation of blood pressure
  http://purl.obolibrary.org/obo/GO_0045777
• thromboxane receptor activity
  http://purl.obolibrary.org/obo/GO_0004960
• G-protein coupled receptor activity
  http://purl.obolibrary.org/obo/GO_0004930
• positive regulation of cytosolic calcium ion concentration
  http://purl.obolibrary.org/obo/GO_0007204
• positive regulation of smooth muscle contraction
  http://purl.obolibrary.org/obo/GO_0045987
• positive regulation of angiogenesis
  http://purl.obolibrary.org/obo/GO_0045766
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• acrosomal vesicle
  http://purl.obolibrary.org/obo/GO_0001669
• positive regulation of vasoconstriction
  http://purl.obolibrary.org/obo/GO_0045907
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• second-messenger-mediated signaling
  http://purl.obolibrary.org/obo/GO_0019932
• regulation of vasoconstriction
  http://purl.obolibrary.org/obo/GO_0019229
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04020
• http://www.genome.jp/dbget-bin/www_bget?map04080

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Calcium signaling pathway
• Neuroactive ligand-receptor interaction