CD17043

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17043

CD17043

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Enpp1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• ectonucleotide pyrophosphatase/phosphodiesterase 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• plasma-cell membrane glycoprotein PC-1
• 1 ectonucleotide pyrophosphatase/phosphodiesterase 1
• E-NPP 1
• lymphocyte antigen 41
• tiptoe walking
• ectonucleotide pyrophosphatase/phosphodiesterase family member 1
• phosphodiesterase I/nucleotide pyrophosphatase 1
• ectonucleotide pyrophosphatase/phosphodiesterase 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• C76301
• twy
• AI428932
• E-NPP1
• Npps
• Ly-41
• Pdnp1
• M6S1
• CD203c
• PC-1
• 4833416E15Rik
• Pca-1
• Pca
• NPP1
• ttw

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18605

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• ectonucleotide pyrophosphatase/phosphodiesterase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97370

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008813

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000037370

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.478860
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.27254

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=173335

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M F. Buckley, et.al., Plasma cell membrane glycoprotein gene Pca-1 (alkaline phosphodiesterase I) is linked to the proto-oncogene Myb on mouse chromosome 10., Immunogenetics, 1992, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/1351877
• N F. Rebbe, et.al., Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1., Proceedings of the National Academy of Sciences of the United States of America, 1991, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/1647027
• Khosrow. Rezvani, et.al., UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19474315
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Pietro. Ciancaglini, et.al., Kinetic analysis of substrate utilization by native and TNAP-, NPP1-, or PHOSPHO1-deficient matrix vesicles., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/19874193
• Ana Maria S. Simão, et.al., Proteoliposomes harboring alkaline phosphatase and nucleotide pyrophosphatase as matrix vesicle biomimetics., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20048161
• Heather H. Zhou, et.al., Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo., European journal of pharmacology, 2009, 616
  http://rdf.ncbi.nlm.nih.gov/pubmed/19577557
• F J. Dumont, et.al., High level expression of the plasma cell antigen PC.1 on the T-cell subset expanding in MRL/MpJ-lpr/lpr mice: detection with a xenogeneic monoclonal antibody and alloantisera., Cellular immunology, 1985, 96
  http://rdf.ncbi.nlm.nih.gov/pubmed/2943419
• M F. Buckley, et.al., Plasma cell membrane glycoprotein PC-1. cDNA cloning of the human molecule, amino acid sequence, and chromosomal location., The Journal of biological chemistry, 1990, 265
  http://rdf.ncbi.nlm.nih.gov/pubmed/2211644
• I R. van Driel, et.al., Murine plasma cell membrane antigen PC-1: molecular cloning of cDNA and analysis of expression., Proceedings of the National Academy of Sciences of the United States of America, 1985, 82
  http://rdf.ncbi.nlm.nih.gov/pubmed/3001713

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• sequestering of triglyceride
  http://purl.obolibrary.org/obo/GO_0030730
• negative regulation of cell growth
  http://purl.obolibrary.org/obo/GO_0030308
• negative regulation of insulin receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0046627
• immune response
  http://purl.obolibrary.org/obo/GO_0006955
• cellular response to insulin stimulus
  http://purl.obolibrary.org/obo/GO_0032869
• phosphate-containing compound metabolic process
  http://purl.obolibrary.org/obo/GO_0006796
• negative regulation of fat cell differentiation
  http://purl.obolibrary.org/obo/GO_0045599
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• nucleic acid binding
  http://purl.obolibrary.org/obo/GO_0003676
• negative regulation of glucose import
  http://purl.obolibrary.org/obo/GO_0046325
• phosphodiesterase I activity
  http://purl.obolibrary.org/obo/GO_0004528
• inorganic diphosphate transport
  http://purl.obolibrary.org/obo/GO_0030505
• generation of precursor metabolites and energy
  http://purl.obolibrary.org/obo/GO_0006091
• nucleoside-triphosphate diphosphatase activity
  http://purl.obolibrary.org/obo/GO_0047429
• negative regulation of glycogen biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045719
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• negative regulation of ossification
  http://purl.obolibrary.org/obo/GO_0030279
• bone remodeling
  http://purl.obolibrary.org/obo/GO_0046849
• scavenger receptor activity
  http://purl.obolibrary.org/obo/GO_0005044
• insulin receptor binding
  http://purl.obolibrary.org/obo/GO_0005158
• nucleotide diphosphatase activity
  http://purl.obolibrary.org/obo/GO_0004551
• polysaccharide binding
  http://purl.obolibrary.org/obo/GO_0030247
• cellular phosphate ion homeostasis
  http://purl.obolibrary.org/obo/GO_0030643
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• biomineral tissue development
  http://purl.obolibrary.org/obo/GO_0031214
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• nucleoside triphosphate catabolic process
  http://purl.obolibrary.org/obo/GO_0009143
• negative regulation of protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0031953
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00500
• http://www.genome.jp/dbget-bin/www_bget?map00760
• http://www.genome.jp/dbget-bin/www_bget?map00230
• http://www.genome.jp/dbget-bin/www_bget?map00740
• http://www.genome.jp/dbget-bin/www_bget?map00770
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Purine metabolism
• Nicotinate and nicotinamide metabolism
• Metabolic pathways
• Pantothenate and CoA biosynthesis
• Starch and sucrose metabolism
• Riboflavin metabolism