CD17061

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17061

CD17061

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Fzd4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• frizzled homolog 4 (Drosophila)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• frizzled-4
• fz-4
• frizzled homolog 4 (Drosophila)
• mFz4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Fz4

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/14366

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• frizzled class receptor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:108520

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008055

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000049791

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.86755

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604579

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Harald J. Junge, et.al., TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling., Cell, 2009, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/19837033
• Nicole M. Collette, et.al., Genetic evidence that SOST inhibits WNT signaling in the limb., Developmental biology, 2010, 342
  http://rdf.ncbi.nlm.nih.gov/pubmed/20359476
• Shuei-Liong. Lin, et.al., Macrophage Wnt7b is critical for kidney repair and regeneration., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20160075
• L C. Sheldahl, et.al., Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner., Current biology : CB, 1999, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/10395542
• Takaaki. Yamada, et.al., Melanocyte stem cells express receptors for canonical Wnt-signaling pathway on their surface., Biochemical and biophysical research communications, 2010, 396
  http://rdf.ncbi.nlm.nih.gov/pubmed/20450888
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Y. Wang, et.al., A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled., The Journal of biological chemistry, 1996, 271
  http://rdf.ncbi.nlm.nih.gov/pubmed/8626800
• T W. Austin, et.al., A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells., Blood, 1997, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/9160667
• U. Borello, et.al., Differential expression of the Wnt putative receptors Frizzled during mouse somitogenesis., Mechanisms of development, 1999, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/10559494
• A. Rattner, et.al., A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9096311

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• retinal blood vessel morphogenesis
  http://purl.obolibrary.org/obo/GO_0061304
• protein heterodimerization activity
  http://purl.obolibrary.org/obo/GO_0046982
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cytokine binding
  http://purl.obolibrary.org/obo/GO_0019955
• regulation of vascular endothelial growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0030947
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• Wnt signaling pathway, calcium modulating pathway
  http://purl.obolibrary.org/obo/GO_0007223
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• PDZ domain binding
  http://purl.obolibrary.org/obo/GO_0030165
• cell projection
  http://purl.obolibrary.org/obo/GO_0042995
• G-protein coupled receptor activity
  http://purl.obolibrary.org/obo/GO_0004930
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• transmembrane signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0004888
• positive regulation of sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0051091
• luteinization
  http://purl.obolibrary.org/obo/GO_0001553
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• substrate adhesion-dependent cell spreading
  http://purl.obolibrary.org/obo/GO_0034446
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0016055
• cerebellum vasculature morphogenesis
  http://purl.obolibrary.org/obo/GO_0061301
• sensory perception of sound
  http://purl.obolibrary.org/obo/GO_0007605
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• embryo development
  http://purl.obolibrary.org/obo/GO_0009790
• Wnt-protein binding
  http://purl.obolibrary.org/obo/GO_0017147
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• locomotion involved in locomotory behavior
  http://purl.obolibrary.org/obo/GO_0031987
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• retina vasculature morphogenesis in camera-type eye
  http://purl.obolibrary.org/obo/GO_0061299
• blood vessel development
  http://purl.obolibrary.org/obo/GO_0001568
• cell surface receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007166
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• negative regulation of cell-substrate adhesion
  http://purl.obolibrary.org/obo/GO_0010812
• canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0060070
• Wnt-activated receptor activity
  http://purl.obolibrary.org/obo/GO_0042813
• extracellular matrix-cell signaling
  http://purl.obolibrary.org/obo/GO_0035426
• vasculogenesis
  http://purl.obolibrary.org/obo/GO_0001570
• progesterone secretion
  http://purl.obolibrary.org/obo/GO_0042701

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05217
• http://www.genome.jp/dbget-bin/www_bget?map04310
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map04916
• http://www.genome.jp/dbget-bin/www_bget?map05166

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Wnt signaling pathway
• Basal cell carcinoma
• HTLV-I infection
• Melanogenesis
• Pathways in cancer