CD17144

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17144

CD17144

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Xcl1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• chemokine (C motif) ligand 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• small inducible cytokine subfamily C, member 1 (lymphotactin)
• c motif chemokine 1
• small-inducible cytokine C1
• cytokine SCM-1
• lymphotaxin
• chemokine (C motif) ligand 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• LTN
• Scyc1
• SCM-1a
• AI661682
• lymphotactin
• ATAC
• Lptn
• SCM-1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16963

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• chemokine (C motif) ligand 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104593

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008510

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000026573

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.190

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600250

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• V. Rumsaeng, et.al., Lymphotactin gene expression in mast cells following Fc(epsilon) receptor I aggregation: modulation by TGF-beta, IL-4, dexamethasone, and cyclosporin A., Journal of immunology (Baltimore, Md. : 1950), 1997, 158
  http://rdf.ncbi.nlm.nih.gov/pubmed/9013979
• J. Kennedy, et.al., Molecular cloning and functional characterization of human lymphotactin., Journal of immunology (Baltimore, Md. : 1950), 1995, 155
  http://rdf.ncbi.nlm.nih.gov/pubmed/7602097
• Brigitte G. Dorner, et.al., Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells., Immunity, 2009, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/19913446
• T. Yoshida, et.al., Molecular cloning of a novel C or gamma type chemokine, SCM-1., FEBS letters, 1995, 360
  http://rdf.ncbi.nlm.nih.gov/pubmed/7875320
• Adrian G. Rosas-Taraco, et.al., Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis., American journal of respiratory cell and molecular biology, 2009, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/19097989
• http://rdf.ncbi.nlm.nih.gov/pubmed/19218235
• J A. Hedrick, et.al., Lymphotactin is produced by NK cells and attracts both NK cells and T cells in vivo., Journal of immunology (Baltimore, Md. : 1950), 1997, 158
  http://rdf.ncbi.nlm.nih.gov/pubmed/9029087
• G S. Kelner, et.al., Lymphotactin: a cytokine that represents a new class of chemokine., Science (New York, N.Y.), 1994, 266
  http://rdf.ncbi.nlm.nih.gov/pubmed/7973732
• Arnaud R. Krebs, et.al., ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes., EMBO reports, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20508642
• Chihiro. Yamazaki, et.al., Conservation of a chemokine system, XCR1 and its ligand, XCL1, between human and mice., Biochemical and biophysical research communications, 2010, 397
  http://rdf.ncbi.nlm.nih.gov/pubmed/20541533

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cell-cell signaling
  http://purl.obolibrary.org/obo/GO_0007267
• CD8-positive, alpha-beta T cell proliferation
  http://purl.obolibrary.org/obo/GO_0035740
• response to virus
  http://purl.obolibrary.org/obo/GO_0009615
• positive regulation of thymocyte migration
  http://purl.obolibrary.org/obo/GO_2000412
• positive regulation of immune response to tumor cell
  http://purl.obolibrary.org/obo/GO_0002839
• positive regulation of natural killer cell chemotaxis
  http://purl.obolibrary.org/obo/GO_2000503
• positive regulation of B cell chemotaxis
  http://purl.obolibrary.org/obo/GO_2000538
• immune response
  http://purl.obolibrary.org/obo/GO_0006955
• T-helper 2 cell cytokine production
  http://purl.obolibrary.org/obo/GO_0035745
• positive regulation of release of sequestered calcium ion into cytosol
  http://purl.obolibrary.org/obo/GO_0051281
• chemokine activity
  http://purl.obolibrary.org/obo/GO_0008009
• positive regulation of leukocyte chemotaxis
  http://purl.obolibrary.org/obo/GO_0002690
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• cellular response to transforming growth factor beta stimulus
  http://purl.obolibrary.org/obo/GO_0071560
• negative regulation of interferon-gamma production
  http://purl.obolibrary.org/obo/GO_0032689
• chemokine receptor binding
  http://purl.obolibrary.org/obo/GO_0042379
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• positive regulation of transforming growth factor beta production
  http://purl.obolibrary.org/obo/GO_0071636
• positive regulation of granzyme B production
  http://purl.obolibrary.org/obo/GO_0071663
• negative regulation of T cell cytokine production
  http://purl.obolibrary.org/obo/GO_0002725
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• negative regulation of T-helper 1 cell activation
  http://purl.obolibrary.org/obo/GO_2000518
• positive regulation of T cell chemotaxis
  http://purl.obolibrary.org/obo/GO_0010820
• lymphocyte chemotaxis
  http://purl.obolibrary.org/obo/GO_0048247
• positive regulation of granzyme A production
  http://purl.obolibrary.org/obo/GO_2000513
• negative regulation of interleukin-2 production
  http://purl.obolibrary.org/obo/GO_0032703
• immunoglobulin production in mucosal tissue
  http://purl.obolibrary.org/obo/GO_0002426
• cytokine activity
  http://purl.obolibrary.org/obo/GO_0005125
• negative regulation of sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0043433
• positive regulation of interleukin-10 production
  http://purl.obolibrary.org/obo/GO_0032733
• positive regulation of neutrophil chemotaxis
  http://purl.obolibrary.org/obo/GO_0090023
• cellular response to interleukin-4
  http://purl.obolibrary.org/obo/GO_0071353
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• positive regulation of innate immune response
  http://purl.obolibrary.org/obo/GO_0045089
• chemotaxis
  http://purl.obolibrary.org/obo/GO_0006935
• positive regulation of T cell cytokine production
  http://purl.obolibrary.org/obo/GO_0002726
• positive regulation of T cell mediated cytotoxicity
  http://purl.obolibrary.org/obo/GO_0001916
• release of sequestered calcium ion into cytosol
  http://purl.obolibrary.org/obo/GO_0051209
• CD4-positive, alpha-beta T cell proliferation
  http://purl.obolibrary.org/obo/GO_0035739
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• T-helper 1 cell cytokine production
  http://purl.obolibrary.org/obo/GO_0035744
• positive regulation of activated T cell proliferation
  http://purl.obolibrary.org/obo/GO_0042104
• regulation of inflammatory response
  http://purl.obolibrary.org/obo/GO_0050727

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04062
• http://www.genome.jp/dbget-bin/www_bget?map04060

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Cytokine-cytokine receptor interaction
• Chemokine signaling pathway