CD17218

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17218

CD17218

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Tph1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• tryptophan hydroxylase 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• tryptophan 5-hydroxylase 1
• tryptophan hydroxylase 1
• tryptophan 5-monooxygenase 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Tph

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/21990

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• tryptophan hydroxylase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98796

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001136084
• https://www.ncbi.nlm.nih.gov/nuccore/NM_009414

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000040046

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.248684

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=191060

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Chen. Liu, et.al., Pet-1 is required across different stages of life to regulate serotonergic function., Nature neuroscience, 2010, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/20818386
• A. Schraenen, et.al., Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy., Diabetologia, 2010, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/20938637
• J. Hanley-Hyde, et.al., Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences., Genomics, 1992, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/1387105
• Paul. Gibson, et.al., Subtypes of medulloblastoma have distinct developmental origins., Nature, 2010, 468
  http://rdf.ncbi.nlm.nih.gov/pubmed/21150899
• Georg. Mellitzer, et.al., Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20364088
• J. Stoll, et.al., Isolation and structural characterization of the murine tryptophan hydroxylase gene., Journal of neuroscience research, 1991, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/1714508
• J. Stoll, et.al., Characterization and chromosomal mapping of a cDNA encoding tryptophan hydroxylase from a mouse mastocytoma cell line., Genomics, 1990, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/2110547
• A V. Kulikov, et.al., [Genetic control of tryptophan hydroxylase activity in the mouse brain]., Genetika, 1983, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/6683693
• Nan. Li, et.al., Serotonin activates dendritic cell function in the context of gut inflammation., The American journal of pathology, 2011, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/21281798
• G E. Reed, et.al., NF-Y activates mouse tryptophan hydroxylase transcription., Brain research, 1995, 682
  http://rdf.ncbi.nlm.nih.gov/pubmed/7552299

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• mammary gland alveolus development
  http://purl.obolibrary.org/obo/GO_0060749
• amino acid binding
  http://purl.obolibrary.org/obo/GO_0016597
• tryptophan 5-monooxygenase activity
  http://purl.obolibrary.org/obo/GO_0004510
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• neuron projection
  http://purl.obolibrary.org/obo/GO_0043005
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• iron ion binding
  http://purl.obolibrary.org/obo/GO_0005506
• bone remodeling
  http://purl.obolibrary.org/obo/GO_0046849
• monooxygenase activity
  http://purl.obolibrary.org/obo/GO_0004497
• aromatic amino acid family metabolic process
  http://purl.obolibrary.org/obo/GO_0009072
• serotonin biosynthetic process
  http://purl.obolibrary.org/obo/GO_0042427
• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
  http://purl.obolibrary.org/obo/GO_0016714
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map00380

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Tryptophan metabolism
• Metabolic pathways