CD17266

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17266

CD17266

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ctsg

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• cathepsin G

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• VSP
• cathepsin G
• vimentin-specific protease

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13035

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• cathepsin G
  http://metadb.riken.jp/db/mgi_rdf/MGI:88563

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007800

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000040314

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.4858

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=116830

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• C R. Abraham, et.al., Expression of cathepsin G-like and alpha 1-antichymotrypsin-like proteins in reactive astrocytes., Brain research, 1993, 621
  http://rdf.ncbi.nlm.nih.gov/pubmed/8242336
• R. Huang, et.al., Genes for mast-cell serine protease and their molecular evolution., Immunogenetics, 1994, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/7959952
• Shuchi. Agrawal-Singh, et.al., Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/20215640
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• J L. Grisolano, et.al., Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 1994, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/8090757
• Geoffrey L. Uy, et.al., A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemia., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20647568
• P A. Hohn, et.al., Genomic organization and chromosomal localization of the human cathepsin G gene., The Journal of biological chemistry, 1989, 264
  http://rdf.ncbi.nlm.nih.gov/pubmed/2569462
• Steffen. Massberg, et.al., Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/20676107
• N. Nakamura, et.al., Purification and characterization of a vimentin-specific protease in mouse myeloid leukemia cells. Regulation during differentiation and identity with cathepsin G., European journal of biochemistry, 1992, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/1577012
• John S. Welch, et.al., Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice., Blood, 2011, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/21190992

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• heparin binding
  http://purl.obolibrary.org/obo/GO_0008201
• serine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008236
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• secretory granule
  http://purl.obolibrary.org/obo/GO_0030141
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• serine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004252
• defense response to fungus
  http://purl.obolibrary.org/obo/GO_0050832
• intermediate filament
  http://purl.obolibrary.org/obo/GO_0005882
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• positive regulation of immune response
  http://purl.obolibrary.org/obo/GO_0050778
• neutrophil mediated killing of gram-positive bacterium
  http://purl.obolibrary.org/obo/GO_0070946
• negative regulation of growth of symbiont in host
  http://purl.obolibrary.org/obo/GO_0044130
• defense response to Gram-positive bacterium
  http://purl.obolibrary.org/obo/GO_0050830
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• response to lipopolysaccharide
  http://purl.obolibrary.org/obo/GO_0032496

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04080
• http://www.genome.jp/dbget-bin/www_bget?map04142
• http://www.genome.jp/dbget-bin/www_bget?map05322
• http://www.genome.jp/dbget-bin/www_bget?map05146
• http://www.genome.jp/dbget-bin/www_bget?map04614

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Systemic lupus erythematosus
• Neuroactive ligand-receptor interaction
• Renin-angiotensin system
• Amoebiasis
• Lysosome