CD17290

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17290

CD17290

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Clec4n

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• C-type lectin domain family 4, member n

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• C-type lectin domain family 6 member A
• dendritic cell-associated C-type lectin 2
• C-type lectin superfamily member 10
• C-type lectin domain family 4, member n
• C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10
• DC-associated C-type lectin 2
• natural killer complex lectin

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Clecsf10
• Nkcl
• Clec6a
• dectin-2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/56620

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• C-type lectin domain family 4, member n
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861231

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001190321
• https://www.ncbi.nlm.nih.gov/nuccore/NM_020001
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001190320

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000023349

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.271782

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=613579

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M. Bonkobara, et.al., Epidermal Langerhans cell-targeted gene expression by a dectin-2 promoter., Journal of immunology (Baltimore, Md. : 1950), 2001, 167
  http://rdf.ncbi.nlm.nih.gov/pubmed/11739507
• C. Carnaud, et.al., Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex., Journal of immunology (Baltimore, Md. : 1950), 2001, 166
  http://rdf.ncbi.nlm.nih.gov/pubmed/11160299
• Shinobu. Saijo, et.al., Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans., Immunity, 2010, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/20493731
• M G. Brown, et.al., Natural killer gene complex (Nkc) allelic variability in inbred mice: evidence for Nkc haplotypes., Immunogenetics, 2001, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/11685471
• Liangkuan. Bi, et.al., CARD9 mediates dectin-2-induced IkappaBalpha kinase ubiquitination leading to activation of NF-kappaB in response to stimulation by the hyphal form of Candida albicans., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20538615
• M J. Fernandes, et.al., Characterization of a novel receptor that maps near the natural killer gene complex: demonstration of carbohydrate binding and expression in hematopoietic cells., Cancer research, 1999, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/10363996
• Kota. Sato, et.al., Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses., The Journal of biological chemistry, 2006, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/17050534
• Nora A. Barrett, et.al., Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells., Journal of immunology (Baltimore, Md. : 1950), 2009, 182
  http://rdf.ncbi.nlm.nih.gov/pubmed/19124755
• K. Ariizumi, et.al., Cloning of a second dendritic cell-associated C-type lectin (dectin-2) and its alternatively spliced isoforms., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10766825
• Matthew J. Robinson, et.al., Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19703985

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• defense response to fungus
  http://purl.obolibrary.org/obo/GO_0050832
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• positive regulation of cytokine secretion
  http://purl.obolibrary.org/obo/GO_0050715
• carbohydrate binding
  http://purl.obolibrary.org/obo/GO_0030246
• binding
  http://purl.obolibrary.org/obo/GO_0005488
• innate immune response
  http://purl.obolibrary.org/obo/GO_0045087
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• positive regulation of I-kappaB kinase/NF-kappaB signaling
  http://purl.obolibrary.org/obo/GO_0043123

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName