CD17314

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17314

CD17314

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Sgcb

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• sarcoglycan, beta (dystrophin-associated glycoprotein)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• sarcoglycan, beta (dystrophin-associated glycoprotein)
• sarcoglycan, beta (43kD dystrophin-associated glycoprotein)
• 43DAG
• beta-sarcoglycan
• 43 kDa dystrophin-associated glycoprotein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI844814
• 43kDa
• AI747103
• beta-SG

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/24051

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• sarcoglycan, beta (dystrophin-associated glycoprotein)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346523

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011890

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029156

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.89310

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600900

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Anh T. Nguyen, et.al., DOT1L regulates dystrophin expression and is critical for cardiac function., Genes & development, 2011, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/21289070
• Stefano. Gastaldello, et.al., Inhibition of proteasome activity promotes the correct localization of disease-causing alpha-sarcoglycan mutants in HEK-293 cells constitutively expressing beta-, gamma-, and delta-sarcoglycan., The American journal of pathology, 2008, 173
  http://rdf.ncbi.nlm.nih.gov/pubmed/18535179
• V. Straub, et.al., epsilon-sarcoglycan replaces alpha-sarcoglycan in smooth muscle to form a unique dystrophin-glycoprotein complex., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10488149
• Laurin M. Hanft, et.al., Cytoplasmic gamma-actin expression in diverse animal models of muscular dystrophy., Neuromuscular disorders : NMD, 2007, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/17475492
• Y M. Chan, et.al., Molecular organization of sarcoglycan complex in mouse myotubes in culture., The Journal of cell biology, 1998, 143
  http://rdf.ncbi.nlm.nih.gov/pubmed/9864373
• Séverine. Groh, et.al., Sarcoglycan complex: implications for metabolic defects in muscular dystrophies., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19494113
• K. Araishi, et.al., Loss of the sarcoglycan complex and sarcospan leads to muscular dystrophy in beta-sarcoglycan-deficient mice., Human molecular genetics, 1999, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/10441321
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• S. Noguchi, et.al., Developmental expression of sarcoglycan gene products in cultured myocytes., Biochemical and biophysical research communications, 1999, 262
  http://rdf.ncbi.nlm.nih.gov/pubmed/10448073
• M. Durbeej, et.al., Disruption of the beta-sarcoglycan gene reveals pathogenetic complexity of limb-girdle muscular dystrophy type 2E., Molecular cell, 2000, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/10678176

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• sarcoglycan complex
  http://purl.obolibrary.org/obo/GO_0016012
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• membrane organization
  http://purl.obolibrary.org/obo/GO_0061024
• cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0007010
• dystrophin-associated glycoprotein complex
  http://purl.obolibrary.org/obo/GO_0016010

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05410
• http://www.genome.jp/dbget-bin/www_bget?map05414
• http://www.genome.jp/dbget-bin/www_bget?map05412
• http://www.genome.jp/dbget-bin/www_bget?map05416

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Arrhythmogenic right ventricular cardiomyopathy (ARVC)
• Dilated cardiomyopathy
• Viral myocarditis
• Hypertrophic cardiomyopathy (HCM)