CD18067

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18067

CD18067

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Gpr143

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• G protein-coupled receptor 143

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• G protein-coupled receptor 143
• MOA1
• G-protein coupled receptor 143
• ocular albinism type 1 protein homolog
• homolog of human ocular albinism 1 (Nettleship-Falls)

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Oa1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18241

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• G protein-coupled receptor 143
  http://metadb.riken.jp/db/mgi_rdf/MGI:107193

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010951

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000025333

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.5157

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=300808

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Francesca. Giordano, et.al., The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition., Human molecular genetics, 2009, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/19717472
• Ilaria. Palmisano, et.al., The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells., Human molecular genetics, 2008, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/18697795
• M B. Dinulos, et.al., A new region of conservation is defined between human and mouse X chromosomes., Genomics, 1996, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/8661129
• E. Montini, et.al., A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin., Human molecular genetics, 1997, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/9215685
• Alejandra. Young, et.al., Involvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formation., Investigative ophthalmology & visual science, 2008, 49
  http://rdf.ncbi.nlm.nih.gov/pubmed/18378571
• J M. Newton, et.al., Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene., Genomics, 1996, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/8921399
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• M T. Bassi, et.al., Cloning of the murine homolog of the ocular albinism type 1 (OA1) gene: sequence, genomic structure, and expression analysis in pigment cells., Genome research, 1996, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/8889556
• Katia. Cortese, et.al., The ocular albinism type 1 (OA1) gene controls melanosome maturation and size., Investigative ophthalmology & visual science, 2005, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/16303920
• H J. Blair, et.al., An integrated genetic and man-mouse comparative map of the DXHXS674-Pdha1 region of the mouse X chromosome., Genomics, 1998, 48
  http://rdf.ncbi.nlm.nih.gov/pubmed/9503026

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• phosphatidylinositol-mediated signaling
  http://purl.obolibrary.org/obo/GO_0048015
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• L-DOPA receptor activity
  http://purl.obolibrary.org/obo/GO_0035643
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• lysosomal membrane
  http://purl.obolibrary.org/obo/GO_0005765
• calcium-mediated signaling using intracellular calcium source
  http://purl.obolibrary.org/obo/GO_0035584
• melanosome localization
  http://purl.obolibrary.org/obo/GO_0032400
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• L-DOPA binding
  http://purl.obolibrary.org/obo/GO_0072544
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• regulation of calcium-mediated signaling
  http://purl.obolibrary.org/obo/GO_0050848
• melanosome
  http://purl.obolibrary.org/obo/GO_0042470
• dopamine binding
  http://purl.obolibrary.org/obo/GO_0035240
• apical plasma membrane
  http://purl.obolibrary.org/obo/GO_0016324
• melanosome organization
  http://purl.obolibrary.org/obo/GO_0032438
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• lysosome
  http://purl.obolibrary.org/obo/GO_0005764
• tyrosine binding
  http://purl.obolibrary.org/obo/GO_0072545
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• G-protein coupled receptor activity
  http://purl.obolibrary.org/obo/GO_0004930
• melanosome membrane
  http://purl.obolibrary.org/obo/GO_0033162
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• melanosome transport
  http://purl.obolibrary.org/obo/GO_0032402

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName