CD18460

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18460

CD18460

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Atn1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• atrophin 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• dentatorubral-pallidoluysian atrophy protein homolog
• atrophin 1
• dentatorubral pallidoluysian atrophy

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• atrophin-1
• Atr1
• Drpla

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13498

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• atrophin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104725

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007881

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000004263

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.333380

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=607462

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Yiguo. Shen, et.al., Functional architecture of atrophins., The Journal of biological chemistry, 2007, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/17150957
• Roland H. Friedel, et.al., EUCOMM--the European conditional mouse mutagenesis program., Briefings in functional genomics & proteomics, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17967808
• M A. Ansari-Lari, et.al., Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6., Genome research, 1998, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/9445485
• M. Oyake, et.al., Molecular cloning of murine homologue dentatorubral-pallidoluysian atrophy (DRPLA) cDNA: strong conservation of a polymorphic CAG repeat in the murine gene., Genomics, 1997, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/9070948
• O. Onodera, et.al., Molecular cloning of a full-length cDNA for dentatorubral-pallidoluysian atrophy and regional expressions of the expanded alleles in the CNS., American journal of human genetics, 1995, 57
  http://rdf.ncbi.nlm.nih.gov/pubmed/7485154
• Chun-Li. Zhang, et.al., Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1., Genes & development, 2006, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/16702404
• Rong. Hou, et.al., Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19131340
• Juehua. Yu, et.al., C-terminal deletion of the atrophin-1 protein results in growth retardation but not neurodegeneration in mice., Developmental dynamics : an official publication of the American Association of Anatomists, 2009, 238
  http://rdf.ncbi.nlm.nih.gov/pubmed/19681162
• G. Schilling, et.al., Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA., Neuron, 1999, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/10677044
• T. Sato, et.al., Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients., Human molecular genetics, 1999, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/9887337

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• transcription corepressor activity
  http://purl.obolibrary.org/obo/GO_0003714
• neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0051402
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• nuclear matrix
  http://purl.obolibrary.org/obo/GO_0016363
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• cell leading edge
  http://purl.obolibrary.org/obo/GO_0031252
• cell migration
  http://purl.obolibrary.org/obo/GO_0016477
• toxin metabolic process
  http://purl.obolibrary.org/obo/GO_0009404
• protein domain specific binding
  http://purl.obolibrary.org/obo/GO_0019904
• regulation of neuron differentiation
  http://purl.obolibrary.org/obo/GO_0045664
• JUN kinase binding
  http://purl.obolibrary.org/obo/GO_0008432
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• http://purl.obolibrary.org/obo/GO_0090729
• regulation of RNA biosynthetic process
  http://purl.obolibrary.org/obo/GO_2001141
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• maintenance of cell polarity
  http://purl.obolibrary.org/obo/GO_0030011

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName