CD18639

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18639

CD18639

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cox4i2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• cytochrome c oxidase subunit IV isoform 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• cytochrome c oxidase subunit 4 isoform 2, mitochondrial
• cytochrome c oxidase subunit IV isoform 2
• cytochrome c oxidase, subunit IVb

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Cox IV-2
• CoxIV-2
• Cox4b

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/84682

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• cytochrome c oxidase subunit 4I2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2135755

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_053091

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000009876

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.196668

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=607976

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Ryo. Fukuda, et.al., HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells., Cell, 2007, 129
  http://rdf.ncbi.nlm.nih.gov/pubmed/17418790
• Michael A. Kiebish, et.al., Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria., Journal of neurochemistry, 2008, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/18373617
• Vamsi K. Mootha, et.al., Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria., Cell, 2003, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/14651853
• Susann. Horvat, et.al., Effect of hypoxia on the transcription pattern of subunit isoforms and the kinetics of cytochrome c oxidase in cortical astrocytes and cerebellar neurons., Journal of neurochemistry, 2006, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/16981895
• Girish V. Putcha, et.al., Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice., The Journal of cell biology, 2002, 157
  http://rdf.ncbi.nlm.nih.gov/pubmed/11980919
• Yoshinori. Takahashi, et.al., Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12370308
• David J. Pagliarini, et.al., A mitochondrial protein compendium elucidates complex I disease biology., Cell, 2008, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/18614015
• Youfen. Li, et.al., Cytochrome c oxidase subunit IV is essential for assembly and respiratory function of the enzyme complex., Journal of bioenergetics and biomembranes, 2006, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/17091399
• M. Hüttemann, et.al., Mammalian subunit IV isoforms of cytochrome c oxidase., Gene, 2001, 267
  http://rdf.ncbi.nlm.nih.gov/pubmed/11311561

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• hydrogen ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_1902600
• cytochrome-c oxidase activity
  http://purl.obolibrary.org/obo/GO_0004129
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• mitochondrial membrane
  http://purl.obolibrary.org/obo/GO_0031966
• mitochondrial inner membrane
  http://purl.obolibrary.org/obo/GO_0005743
• ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034220
• mitochondrial respiratory chain complex IV
  http://purl.obolibrary.org/obo/GO_0005751
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05012
• http://www.genome.jp/dbget-bin/www_bget?map05016
• http://www.genome.jp/dbget-bin/www_bget?map00190
• http://www.genome.jp/dbget-bin/www_bget?map05010
• http://www.genome.jp/dbget-bin/www_bget?map04260
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Metabolic pathways
• Parkinson's disease
• Alzheimer's disease
• Huntington's disease
• Oxidative phosphorylation
• Cardiac muscle contraction