CD18661

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18661

CD18661

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Kcnmb1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• potassium large conductance calcium-activated channel, subfamily M, beta member 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• BKbeta
• slo-beta
• maxi K channel subunit beta-1
• BK channel subunit beta-1
• calcium-activated potassium channel subunit beta
• potassium large conductance calcium-activated channel, subfamily M, beta member 1
• calcium-activated potassium channel, subfamily M subunit beta-1
• calcium-activated potassium channel subunit beta-1
• charybdotoxin receptor subunit beta-1
• k(VCA)beta-1
• slo-beta-1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• BKbeta1
• BK channel beta subunit

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16533

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• potassium large conductance calcium-activated channel, subfamily M, beta member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1334203

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_031169

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000020155

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.6206

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603951

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• P Richard. Grimm, et.al., Hypertension of Kcnmb1-/- is linked to deficient K secretion and aldosteronism., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19556540
• Lucía. Bautista, et.al., Hypoxia inducible factor-2alpha stabilization and maxi-K+ channel beta1-subunit gene repression by hypoxia in cardiac myocytes: role in preconditioning., Circulation research, 2009, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/19461047
• Hui. Xu, et.al., Large-conductance Ca2+-activated K+ channel beta1-subunit knockout mice are not hypertensive., American journal of physiology. Heart and circulatory physiology, 2011, 300
  http://rdf.ncbi.nlm.nih.gov/pubmed/21131476
• Xiaochun. Long, et.al., The smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19801679
• R. Brenner, et.al., Vasoregulation by the beta1 subunit of the calcium-activated potassium channel., Nature, 2000, 407
  http://rdf.ncbi.nlm.nih.gov/pubmed/11057658
• G V. Petkov, et.al., Beta1-subunit of the Ca2+-activated K+ channel regulates contractile activity of mouse urinary bladder smooth muscle., The Journal of physiology, 2001, 537
  http://rdf.ncbi.nlm.nih.gov/pubmed/11731577
• G M. Dick, et.al., (Xeno)estrogen sensitivity of smooth muscle BK channels conferred by the regulatory beta1 subunit: a study of beta1 knockout mice., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11590153
• Z. Jiang, et.al., Human and rodent MaxiK channel beta-subunit genes: cloning and characterization., Genomics, 1999, 55
  http://rdf.ncbi.nlm.nih.gov/pubmed/9888999
• S. Plüger, et.al., Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca(2+) spark/STOC coupling and elevated blood pressure., Circulation research, 2000, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/11090555

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034220
• calcium-activated potassium channel activity
  http://purl.obolibrary.org/obo/GO_0015269
• ion channel activity
  http://purl.obolibrary.org/obo/GO_0005216
• potassium channel regulator activity
  http://purl.obolibrary.org/obo/GO_0015459
• response to calcium ion
  http://purl.obolibrary.org/obo/GO_0051592
• potassium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0071805
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• potassium ion transport
  http://purl.obolibrary.org/obo/GO_0006813
• voltage-gated potassium channel complex
  http://purl.obolibrary.org/obo/GO_0008076
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• membrane
  http://purl.obolibrary.org/obo/GO_0016020

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04270

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Vascular smooth muscle contraction