CD19300

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19300

CD19300

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Thrb

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• thyroid hormone receptor beta

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• c-erbA-beta
• thyroid hormone receptor beta
• nuclear receptor subfamily 1 group A member 2
• c-erbA-2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• T3R[b]
• c-erbAbeta
• TR beta
• Thrb1
• T3Rbeta
• Nr1a2
• Thrb2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/21834

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• thyroid hormone receptor beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:98743

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001113417
• https://www.ncbi.nlm.nih.gov/nuccore/NM_009380

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000021779

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.32563

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=190160

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• W M. Wood, et.al., Structural and functional characterization of the genomic locus encoding the murine beta 2 thyroid hormone receptor., Molecular endocrinology (Baltimore, Md.), 1994, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/7708051
• Akishi. Onishi, et.al., Pias3-dependent SUMOylation controls mammalian cone photoreceptor differentiation., Nature neuroscience, 2010, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/20729845
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Julia. Grizenkova, et.al., The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/21151910
• Richa. Kapoor, et.al., Loss of thyroid hormone receptor β is associated with increased progenitor proliferation and NeuroD positive cell number in the adult hippocampus., Neuroscience letters, 2011, 487
  http://rdf.ncbi.nlm.nih.gov/pubmed/20959135
• I. Issemann, et.al., Cloning of novel members of the steroid hormone receptor superfamily., The Journal of steroid biochemistry and molecular biology, 1991, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/1958530
• L. Ng, et.al., N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone., Molecular endocrinology (Baltimore, Md.), 1995, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/7491112
• A J. Hörlein, et.al., Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor., Nature, 1995, 377
  http://rdf.ncbi.nlm.nih.gov/pubmed/7566114
• Kimiko. Katoh, et.al., Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20463215
• W M. Wood, et.al., Isolation and characterization of mouse complementary DNAs encoding alpha and beta thyroid hormone receptors from thyrotrope cells: the mouse pituitary-specific beta 2 isoform differs at the amino terminus from the corresponding species from rat pituitary tumor cells., Molecular endocrinology (Baltimore, Md.), 1991, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/1944303

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• double-stranded DNA binding
  http://purl.obolibrary.org/obo/GO_0003690
• regulation of cholesterol metabolic process
  http://purl.obolibrary.org/obo/GO_0090181
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• steroid hormone receptor activity
  http://purl.obolibrary.org/obo/GO_0003707
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• regulation of triglyceride metabolic process
  http://purl.obolibrary.org/obo/GO_0090207
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• sensory perception of sound
  http://purl.obolibrary.org/obo/GO_0007605
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• thyroid hormone receptor activity
  http://purl.obolibrary.org/obo/GO_0004887
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• steroid hormone mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0043401
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• regulation of lipid metabolic process
  http://purl.obolibrary.org/obo/GO_0019216
• positive regulation of chondrocyte differentiation
  http://purl.obolibrary.org/obo/GO_0032332
• positive regulation of ossification
  http://purl.obolibrary.org/obo/GO_0045778
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• regulation of heart contraction
  http://purl.obolibrary.org/obo/GO_0008016
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• enzyme binding
  http://purl.obolibrary.org/obo/GO_0019899
• negative regulation of female receptivity
  http://purl.obolibrary.org/obo/GO_0007621
• female courtship behavior
  http://purl.obolibrary.org/obo/GO_0008050

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04080

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Neuroactive ligand-receptor interaction